Gene: EEF1A2
Official Full Name: eukaryotic translation elongation factor 1 alpha 2provided by HGNC
Gene Summary: This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. [provided by RefSeq, Mar 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38111 | EEF1A2 Knockout cell line (HeLa) | Human | EEF1A2 | 1:3~1:6 | Negative | Online Inquiry |
KO38112 | EEF1A2 Knockout cell line (HCT 116) | Human | EEF1A2 | 1:2~1:4 | Negative | Online Inquiry |
KO38113 | EEF1A2 Knockout cell line (HEK293) | Human | EEF1A2 | 1:3~1:6 | Negative | Online Inquiry |
KO38114 | EEF1A2 Knockout cell line (A549) | Human | EEF1A2 | 1:3~1:4 | Negative | Online Inquiry |
EEF1A2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the EEF1A2 gene, which encodes the eukaryotic elongation factor 1 alpha 2. This gene plays a crucial role in the translation process by facilitating the delivery of aminoacyl-tRNA to the ribosome, thus influencing protein synthesis. By utilizing genetic engineering techniques such as CRISPR-Cas9, these knockout cell lines allow researchers to investigate the functional implications of EEF1A2 depletion on cellular metabolism, proliferation, and disease states.
The primary mechanism of action of EEF1A2 Gene Knockout Cell Lines involves the elimination of EEF1A2 protein production, which can lead to alterations in protein synthesis dynamics, cellular stress responses, and potentially aberrant cellular behaviors associated with various pathologies, including cancer. Such models provide indispensable insights into the biological role of EEF1A2 in cell signaling and growth, paving the way for novel therapeutic strategies targeting translation-related pathways.
In a scientific context, these knockout cell lines are invaluable for researchers seeking to elucidate the molecular underpinnings of diseases, develop targeted therapies, or explore the consequences of altered protein synthesis in cellular contexts. Their applications span diverse fields, including oncology, neurobiology, and immunology, making them a versatile addition to the research toolkit.
What sets EEF1A2 Gene Knockout Cell Lines apart is their specificity and reliability; unlike traditional models, these lines offer a controlled environment that precisely replicates the absence of EEF1A2, minimizing off-target effects and enhancing reproducibility in experimental outcomes. Moreover, these cell lines can be adapted for high-throughput screening, increasing their utility for both academic and pharmaceutical research.
Researchers and clinicians will find significant value in incorporating EEF1A2 Gene Knockout Cell Lines into their studies, as they provide crucial insights into gene function, disease mechanisms, and therapeutic avenues. This innovative product taps into your research inquiries and assists in the pursuit of scientific knowledge that can lead to the next breakthroughs in healthcare.
Our company boasts extensive expertise in cellular model development, combining cutting-edge technology with a commitment to providing high-quality biological products tailored to meet the specific needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.