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EDC4 Knockout Cell Lines

Gene: EDC4

Official Full Name: enhancer of mRNA decapping 4provided by HGNC

Gene Summary: Predicted to be involved in deadenylation-independent decapping of nuclear-transcribed mRNA. Located in P-body and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00193 EDC4 gRNA1-gRNA2 KO plasmid EDC4 $850
KO04064 EDC4 Knockout cell line (HeLa) Human EDC4 1:3~1:6 Negative Online Inquiry
KO04065 EDC4 Knockout cell line (HCT 116) Human EDC4 1:2~1:4 Negative Online Inquiry
KO04066 EDC4 Knockout cell line (HEK293) Human EDC4 1:3~1:6 Negative Online Inquiry
KO04067 EDC4 Knockout cell line (A549) Human EDC4 1:3~1:4 Negative Online Inquiry

Background

EDC4 Gene Knockout Cell Lines are genetically modified cellular models where the EDC4 gene has been selectively disrupted, enabling researchers to investigate the biological functions and pathways related to RNA binding and post-transcriptional regulation. EDC4, also known as Enhancer of mRNA Decapping 4, is crucial in the regulation of mRNA stability and turnover, which are essential processes in gene expression control. By creating a knockout model, the specific influence of EDC4 on various cellular processes can be elucidated.

The mechanisms by which EDC4 influences these processes involve its role in the deadenylation and decapping of mRNA, affecting the rate of mRNA degradation and ultimately modulating protein synthesis. Researchers utilizing EDC4 Gene Knockout Cell Lines can explore how disruptions in this gene impact various cellular functions, including stress response, signaling pathways, and developmental processes. This is particularly valuable for studying diseases where mRNA stability is perturbed, such as certain cancers or neurodegenerative disorders.

One key scientific advantage of the EDC4 knockout model is the specificity of the gene application; it allows for the dissection of EDC4-related pathways without the confounding effects that might arise from functional redundancy often seen in wild-type systems. Additionally, these cell lines can be employed in high-throughput screening applications for pharmacological interventions or in the development of targeted therapeutics.

For researchers and clinicians, the value of EDC4 Gene Knockout Cell Lines lies not only in their application for mechanistic studies but also in their potential to provide novel insights leading to innovative treatment strategies. The reduced background noise in pathways allows for a clearer signal detection when probing gene interactions and effects.

Our company prides itself on delivering high-quality, reliable biological products tailored for advanced research. With extensive expertise in genetic engineering and cellular biology, we ensure that EDC4 Gene Knockout Cell Lines meet stringent quality control standards, facilitating impactful scientific discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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