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DZIP1L Knockout Cell Lines

Gene: DZIP1L

Official Full Name: DAZ interacting zinc finger protein 1 likeprovided by HGNC

Gene Summary: Predicted to enable metal ion binding activity. Involved in cilium assembly and regulation of protein localization. Located in centriole and ciliary basal body. Implicated in polycystic kidney disease 5. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21322 DZIP1L Knockout cell line (HeLa) Human DZIP1L 1:3~1:6 Negative Online Inquiry
KO21323 DZIP1L Knockout cell line (HCT 116) Human DZIP1L 1:2~1:4 Negative Online Inquiry
KO21324 DZIP1L Knockout cell line (HEK293) Human DZIP1L 1:3~1:6 Negative Online Inquiry
KO21325 DZIP1L Knockout cell line (A549) Human DZIP1L 1:3~1:4 Negative Online Inquiry

Background

DZIP1L Gene Knockout Cell Lines are sophisticated laboratory models specifically designed to enable the study of the DZIP1L gene's function in various biological processes. These cell lines have been created through precise genome editing techniques, such as CRISPR/Cas9, to completely remove the DZIP1L gene, allowing researchers to investigate the resultant phenotypic changes and molecular mechanisms at play without the interference of this gene.

The key function of DZIP1L involves participating in the regulation of cellular signaling pathways, particularly those linked to neuronal function and development. By utilizing these knockout cell lines, scientists can gain valuable insights into how alterations in DZIP1L expression affect cell behavior, gene expression profiles, and interaction with other signaling molecules. Such studies are crucial for understanding the underlying mechanisms of various diseases, including neurodegenerative disorders and other conditions where DZIP1L may play a role.

The scientific importance of DZIP1L Gene Knockout Cell Lines extends into both basic and applied research. In clinical settings, these cell lines offer potential for identifying new therapeutic targets and for drug discovery efforts aimed at conditions linked to dysfunctional DZIP1L activity. Furthermore, these models serve as invaluable tools in genetics, cellular biology, and pharmacology, facilitating advancements in precision medicine.

Compared to traditional cell lines that retain the DZIP1L gene, DZIP1L Gene Knockout Cell Lines provide a unique advantage: they allow for a clearer assessment of gene function with reduced complexity from confounding factors. This isolation of gene-specific effects enhances the reliability of research outcomes and speeds up the translation of findings into clinical applications.

For researchers and clinicians alike, the value of DZIP1L Gene Knockout Cell Lines lies in their ability to streamline investigations that require precise genetic modifications, ultimately contributing to breakthroughs in understanding and treating complex biological phenomena. Our company is dedicated to providing high-quality biological products that meet the rigorous standards of scientific research, backed by years of expertise in genetic engineering and cell biology.

Please note that all services are for research use only. Not intended for any clinical use.

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