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DSCC1 Knockout Cell Lines

Gene: DSCC1

Official Full Name: DNA replication and sister chromatid cohesion 1provided by HGNC

Gene Summary: CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).[supplied by OMIM, Dec 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18156 DSCC1 Knockout cell line (HeLa) Human DSCC1 1:3~1:6 Negative Online Inquiry
KO18157 DSCC1 Knockout cell line (HCT 116) Human DSCC1 1:2~1:4 Negative Online Inquiry
KO18158 DSCC1 Knockout cell line (HEK293) Human DSCC1 1:3~1:6 Negative Online Inquiry
KO18159 DSCC1 Knockout cell line (A549) Human DSCC1 1:3~1:4 Negative Online Inquiry

Background

DSCC1 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the function of the DSCC1 gene and its role in various biological processes, including DNA repair and replication. These knockout cell lines have had the DSCC1 gene selectively inactivated, allowing researchers to investigate downstream effects on cellular mechanisms, gene expression, and overall cellular behavior without the interference of the DSCC1 protein.

The significance of the DSCC1 knockout cell lines lies in their ability to elucidate the biological pathways influenced by the DSCC1 gene. By utilizing these models, scientists can study the consequences of DSCC1 deficiency, examine its contributions to genomic stability, and explore its implications in cancer development and progression. The knockout model is pivotal for developing targeted therapeutic strategies, particularly in oncology, where understanding the genetic underpinnings of tumor behavior is essential.

One of the primary advantages of our DSCC1 Gene Knockout Cell Lines is their high specificity and reproducibility, enabling researchers to obtain consistent results. Unlike other gene-editing approaches, which may yield off-target effects, our knockout lines are rigorously validated for their specificity and represent a reliable model for various assays. Furthermore, these cell lines are compatible with high-throughput screening techniques, making them ideal for large-scale studies.

Researchers and clinicians seeking to advance their understanding of cancer biology or genetic repair mechanisms will find these cell lines invaluable. The DSCC1 knockout models not only facilitate a direct examination of gene function but also represent a critical tool for drug discovery and validation in research settings.

At our company, we pride ourselves on our commitment to supplying high-quality biological products backed by extensive research and development. Our expertise in gene editing and cell line generation ensures that scientists have access to robust and innovative tools that propel their research forward.

Please note that all services are for research use only. Not intended for any clinical use.

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