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DOP1A Knockout Cell Lines

Gene: DOP1A

Official Full Name: DOP1 leucine zipper like protein Aprovided by HGNC

Gene Summary: Predicted to be involved in Golgi to endosome transport and endoplasmic reticulum organization. Predicted to be located in Golgi membrane. Predicted to be active in endosome and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03303 DOP1A Knockout cell line (HeLa) Human DOP1A 1:3~1:6 Negative Online Inquiry
KO03304 DOP1A Knockout cell line (HCT 116) Human DOP1A 1:2~1:4 Negative Online Inquiry
KO03305 DOP1A Knockout cell line (HEK293) Human DOP1A 1:3~1:6 Negative Online Inquiry
KO03306 DOP1A Knockout cell line (A549) Human DOP1A 1:3~1:4 Negative Online Inquiry

Background

DOP1A Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the DOP1A gene function by providing a platform where this gene has been intentionally disrupted. This strategic knockout allows researchers to investigate the role of DOP1A in various biological processes, including neurotransmission, signal transduction, and cellular responses to external stimuli. The engineered cell lines utilize CRISPR-Cas9 technology, a cutting-edge gene-editing mechanism, ensuring precise and efficient knockout of the target gene without off-target effects.

These cell lines offer researchers invaluable insights into the pathophysiological roles and potential therapeutic implications of DOP1A in various diseases, particularly neurodegenerative disorders and psychiatric conditions. By elucidating the DOP1A gene's function, scientific investigations can lead to novel drug targets and treatment strategies. The ability to model human disease conditions in vitro through these cell lines also enhances translational research, allowing for more efficient testing of pharmaceutical compounds and biological therapeutics.

Compared to traditional gene knockout models, DOP1A Gene Knockout Cell Lines significantly reduce the time and materials needed for gene editing, while also minimizing the variability inherent in animal models. Their use in high-throughput screening and functional assays makes them particularly appealing, as they provide reproducible data and can be easily manipulated to create various experimental conditions.

The scientific community stands to benefit greatly from these cell lines, as they bridge the gap between basic research and clinical application. By enabling more focused investigations into the DOP1A gene, researchers and clinicians alike can harness these tools to drive discoveries that may ultimately lead to improved patient outcomes. Our company prides itself on providing high-quality biological products, backed by extensive expertise and dedication to supporting advancement in molecular biology research.

Please note that all services are for research use only. Not intended for any clinical use.

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