Gene: DOCK11
Official Full Name: dedicator of cytokinesis 11provided by HGNC
Gene Summary: Predicted to enable guanyl-nucleotide exchange factor activity. Involved in positive regulation of filopodium assembly. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25834 | DOCK11 Knockout cell line (HeLa) | Human | DOCK11 | 1:3~1:6 | Negative | Online Inquiry |
KO25835 | DOCK11 Knockout cell line (HEK293) | Human | DOCK11 | 1:3~1:6 | Negative | Online Inquiry |
KO25836 | DOCK11 Knockout cell line (A549) | Human | DOCK11 | 1:3~1:4 | Negative | Online Inquiry |
DOCK11 Gene Knockout Cell Lines represent a pioneering advancement in the field of molecular biology, specifically designed to facilitate research related to cellular signaling pathways and developmental processes. DOCK11 (Dedicator of Cytokinesis 11) is a member of the DOCK family of proteins, which are integral to actin cytoskeleton dynamics and cellular motility. The creation of knockout cell lines allows researchers to effectively eliminate the expression of the DOCK11 gene, enabling the study of its functional role and implications in various biological processes and diseases.
These cell lines employ the CRISPR/Cas9 genome-editing technology, a precise and robust mechanism that induces targeted double-strand breaks in DNA, resulting in the deletion of the DOCK11 gene. The loss of DOCK11 expression permits the elucidation of its contributions to processes such as cell migration, adhesion, and proliferation. By observing cellular behavior post-knockout, researchers can gain critical insights into the molecular pathways involved in cancer metastasis, immune responses, and developmental biology.
The scientific importance of DOCK11 Gene Knockout Cell Lines cannot be overstated, as they serve as valuable tools in both basic and applied research. They are pivotal in drug discovery initiatives, allowing for the identification of novel therapeutic targets, and are also instrumental in exploring genetic underpinnings of various pathologies. Moreover, their utility extends into the clinical realm, aiding researchers in the development of personalized medicine strategies.
Compared to conventional knockout models, the DOCK11 Gene Knockout Cell Lines offer superior reproducibility and ease of use, streamlining experimental workflows and thereby accelerating discovery. Researchers benefit significantly from their ability to generate consistent, high-quality results that enhance experimental validity.
For researchers and clinicians keen on investigating the complexities of cell biology, the DOCK11 Gene Knockout Cell Lines represent an invaluable asset that opens avenues for innovative research and therapeutic development. Our company is committed to delivering high-quality biological products, backed by expertise and experience in advancing scientific exploration and application.
Please note that all services are for research use only. Not intended for any clinical use.
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