Gene: DNM3
Official Full Name: dynamin 3provided by HGNC
Gene Summary: This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07691 | DNM3 Knockout cell line (HeLa) | Human | DNM3 | 1:3~1:6 | Negative | Online Inquiry |
KO07692 | DNM3 Knockout cell line (HCT 116) | Human | DNM3 | 1:2~1:4 | Negative | Online Inquiry |
KO07693 | DNM3 Knockout cell line (HEK293) | Human | DNM3 | 1:3~1:6 | Negative | Online Inquiry |
KO07694 | DNM3 Knockout cell line (A549) | Human | DNM3 | 1:3~1:4 | Negative | Online Inquiry |
DNM3 Gene Knockout Cell Lines represent a cutting-edge biological research tool designed to facilitate the study of the dynamin 3 gene (DNM3), which is integral to cellular processes such as endocytosis, synaptic vesicle trafficking, and mitochondrial function. The DNM3 knockout model provides researchers with a unique opportunity to explore the physiological and pathological roles of DNM3 by observing cellular behavior in its absence, thereby unveiling the gene's contribution to critical processes in both normal physiology and disease states.
These engineered cell lines function by employing CRISPR/Cas9 technology to precisely disrupt the DNM3 gene, resulting in a loss of function that enables comprehensive analyses of downstream effects. Researchers can investigate alterations in signaling pathways, vesicle formation, and cellular morphology, providing unparalleled insights into disorders linked to DNM3 dysregulation, such as neurological diseases and cancer.
The scientific importance of DNM3 Gene Knockout Cell Lines is evident in their ability to serve as robust models for drug discovery, genetic analysis, and functional genomics. These cell lines can be utilized in high-throughput screening assays to identify compounds that may restore normal function or mitigate disease symptoms, thus expediting the journey from bench to bedside.
Compared to alternative models, such as wild-type cells or overexpression systems, DNM3 knockout lines offer distinctly greater specificity in delineating gene function and interaction networks. They allow for better assessment of phenotypes that are directly attributable to the absence of DNM3, minimizing confounding variables often present in other methodologies.
For researchers and clinicians alike, DNM3 Gene Knockout Cell Lines provide a valuable asset that can enhance experimental precision, promote new discoveries, and ultimately lead to more effective therapeutic interventions. Backed by our company's commitment to advancing genetic research, we ensure that each cell line is validated for functionality and consistency, empowering you to explore complex biological questions with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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