Gene: DNAJC3
Official Full Name: DnaJ heat shock protein family (Hsp40) member C3provided by HGNC
Gene Summary: This gene encodes a protein with multiple tetratricopeptide repeat (TPR) motifs as well as the highly conserved J domain found in DNAJ chaperone family members. It is a member of the tetratricopeptide repeat family of proteins and acts as an inhibitor of the interferon-induced, dsRNA-activated protein kinase (PKR). [provided by RefSeq, Jul 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35912 | DNAJC3 Knockout cell line (HeLa) | Human | DNAJC3 | 1:3~1:6 | Negative | Online Inquiry |
KO35913 | DNAJC3 Knockout cell line (HCT 116) | Human | DNAJC3 | 1:2~1:4 | Negative | Online Inquiry |
KO35914 | DNAJC3 Knockout cell line (HEK293) | Human | DNAJC3 | 1:3~1:6 | Negative | Online Inquiry |
KO35915 | DNAJC3 Knockout cell line (A549) | Human | DNAJC3 | 1:3~1:4 | Negative | Online Inquiry |
DNAJC3 Gene Knockout Cell Lines are genetically modified cell lines that have had the DNAJC3 gene selectively disrupted, enabling researchers to investigate the specific functions and biological roles of this gene in various cellular processes. DNAJC3, a member of the DnaJ/Hsp40 family of proteins, plays a crucial role in protein folding and the cellular stress response, and its knockout provides a valuable tool for studying intricate cellular mechanisms related to protein homeostasis and disease pathology.
The primary function of these cell lines is to enable comprehensive analyses of the DNAJC3 gene’s contributions to cellular stress responses, including those associated with neurodegenerative diseases, cancer, and metabolic disorders. By utilizing gene knockout techniques, such as CRISPR/Cas9, researchers can delineate pathways affected by the absence of DNAJC3, ultimately leading to insights into molecular mechanisms that can be crucial for therapeutic development.
In the research landscape, the implications of studying DNAJC3 knockout cell lines are significant, as they can aid in the identification of potential biomarkers and therapeutic targets. In clinical settings, understanding the role of DNAJC3 could contribute to advancements in regenerative medicine and cancer therapeutics, enriching the precision of treatments tailored to specific genetic backgrounds.
What sets our DNAJC3 Gene Knockout Cell Lines apart from alternatives is their high efficacy, reproducibility, and compliance with rigorous quality control standards. Each cell line is validated for specific knockout success, ensuring researchers can rely on their integrity for experimental designs. Moreover, these cell lines are provided with comprehensive documentation and support to facilitate optimal experimental outcomes.
For researchers and clinicians alike, investing in our DNAJC3 Gene Knockout Cell Lines translates to high-quality data and enhanced experimental success rates. By choosing our products, users are not just accessing cutting-edge technology but leveraging our extensive expertise in genetic engineering and cell biology. Our commitment is to empower scientific discovery and therapeutic innovation through our range of meticulously developed biological products.
Please note that all services are for research use only. Not intended for any clinical use.
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