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DNAJC16 Knockout Cell Lines

Gene: DNAJC16

Official Full Name: DnaJ heat shock protein family (Hsp40) member C16provided by HGNC

Gene Summary: Involved in regulation of autophagosome size. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29416 DNAJC16 Knockout cell line (HeLa) Human DNAJC16 1:3~1:6 Negative Online Inquiry
KO29417 DNAJC16 Knockout cell line (HCT 116) Human DNAJC16 1:2~1:4 Negative Online Inquiry
KO29418 DNAJC16 Knockout cell line (HEK293) Human DNAJC16 1:3~1:6 Negative Online Inquiry
KO29419 DNAJC16 Knockout cell line (A549) Human DNAJC16 1:3~1:4 Negative Online Inquiry

Background

DNAJC16 Gene Knockout Cell Lines are a cutting-edge biological research tool designed to facilitate the study of cellular processes and disease mechanisms by specifically targeting and disrupting the DNAJC16 gene. The DNAJC16 gene encodes a member of the DnaJ heat shock protein family, involved in protein folding and cellular stress responses. By employing CRISPR-Cas9 gene editing technology, these knockout cell lines provide a unique platform for researchers to study the functional implications of DNAJC16 loss, enabling the exploration of its role in various physiological and pathological conditions, including neurodegeneration and cancer.

The primary mechanism of action relies on the precise elimination of the DNAJC16 gene, leading to the absence of its protein product in the resultant cell lines. This genetic modification allows researchers to observe differences in cellular behavior, signaling pathways, and stress responses compared to wild-type cells. Such insights are crucial for understanding gene function and the underlying mechanisms of diseases linked to DNAJC16 dysregulation.

From a scientific standpoint, these cell lines are invaluable in both basic and applied research settings. They can be utilized to investigate molecular pathways, test therapeutic strategies, and analyze drug responses, particularly in the context of diseases associated with mitochondrial function and proteostasis. The availability of these knockout models enables researchers to accelerate their findings and contribute significantly to the field of molecular biology.

One of the standout advantages of DNAJC16 Gene Knockout Cell Lines is their specificity and reliability, significantly reducing off-target effects compared to other gene-editing methods. Furthermore, these cell lines come with comprehensive characterizations, including genotyping data and validation of gene disruption, ensuring that researchers can depend on these models for reproducible results.

For researchers, clinicians, and academic institutions focused on understanding the complexities of gene functions and their implications for health and disease, our DNAJC16 Gene Knockout Cell Lines present an exceptional opportunity. They provide an essential resource to deepen insights into both fundamental biological processes and the development of innovative therapeutic approaches.

Our company is dedicated to advancing scientific knowledge through high-quality biological products. With a robust portfolio of gene-editing models and validated tools, we are committed to supporting the research community in their quest to elucidate the mechanisms of disease and develop effective treatments.

Please note that all services are for research use only. Not intended for any clinical use.

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