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DMXL1 Knockout Cell Lines

Gene: DMXL1

Official Full Name: Dmx like 1provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the WD repeat superfamily of proteins, which have regulatory functions. This gene is expressed in many tissue types including several types of eye tissue, and it has been associated with ocular phenotypes. In addition, it is upregulated in cultured cells that overexpress growth factor independence 1B, a transcription factor that is essential for hematopoietic cell development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38258 DMXL1 Knockout cell line (HeLa) Human DMXL1 1:3~1:6 Negative Online Inquiry
KO38259 DMXL1 Knockout cell line (HCT 116) Human DMXL1 1:2~1:4 Negative Online Inquiry
KO38260 DMXL1 Knockout cell line (HEK293) Human DMXL1 1:3~1:6 Negative Online Inquiry
KO38261 DMXL1 Knockout cell line (A549) Human DMXL1 1:3~1:4 Negative Online Inquiry

Background

DMXL1 Gene Knockout Cell Lines are specifically engineered cellular models that allow researchers to study the function of the DMXL1 gene by providing a complete knockout of its expression. Through advanced CRISPR-Cas9 technology, these cell lines ensure the precise and efficient disruption of the DMXL1 gene, enabling scientists to investigate the subsequent phenotypic alterations without the confounding effects of the gene's normal expression.

The primary function of DMXL1 is implicated in various cellular processes, including transcriptional regulation, which exerts influence over gene expression levels and cellular responses. By utilizing these knockout cell lines, researchers can elucidate the impact of DMXL1 on cellular pathways, immune responses, and developmental processes, thus providing critical insights into its role in pathological conditions or during cellular stress. This makes DMXL1 Gene Knockout Cell Lines highly valuable in both basic and applied research settings, particularly in the fields of genetics, molecular biology, and therapeutics.

Compared to existing alternatives, such as traditional knockdown methods using siRNA or shRNA, which can lead to incomplete or transient effects, DMXL1 Gene Knockout Cell Lines offer a more stable and irreversible gene disruption, enabling prolonged studies without variability in gene expression over time. Additionally, these cell lines are rigorously validated for specificity and performance, ensuring reliability in experimental outcomes.

This product is not only an essential tool for researchers seeking to unravel the complexities of genetic regulation but also vastly beneficial for clinicians aiming to develop targeted therapies for diseases linked to DMXL1 dysregulation. The ability to create reproducible, knockout models fundamentally enhances experimental design, paving the way for innovative discoveries and applications.

At our company, we pride ourselves on our commitment to excellence in genetic engineering and cellular biology. With a strong background in biotechnological research and product development, we provide scientists with tools that facilitate groundbreaking advancements in understanding gene function and the development of therapeutics.

Please note that all services are for research use only. Not intended for any clinical use.

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