Gene: DISP1
Official Full Name: dispatched RND transporter family member 1provided by HGNC
Gene Summary: The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10077 | DISP1 Knockout cell line (HeLa) | Human | DISP1 | 1:3~1:6 | Negative | Online Inquiry |
KO10078 | DISP1 Knockout cell line (HCT 116) | Human | DISP1 | 1:2~1:4 | Negative | Online Inquiry |
KO10079 | DISP1 Knockout cell line (HEK293) | Human | DISP1 | 1:3~1:6 | Negative | Online Inquiry |
KO10080 | DISP1 Knockout cell line (A549) | Human | DISP1 | 1:3~1:4 | Negative | Online Inquiry |
DISP1 Gene Knockout Cell Lines are precision-engineered cellular models specifically designed to investigate the role of the DISP1 gene in various biological processes and diseases. By employing CRISPR/Cas9 technology, these cell lines have undergone targeted gene editing to effectively eliminate the expression of the DISP1 gene, allowing researchers to study the phenotypic and molecular consequences of its absence.
The key function of DISP1 is to encode a protein involved in the regulation of signaling pathways essential for cellular growth, differentiation, and developmental processes. The DISP1 Gene Knockout Cell Lines provide invaluable insights into these pathways by facilitating the analysis of cellular responses in the absence of normal DISP1 function. This allows scientists to explore the gene's implications in developmental disorders, cancer progression, and other pathological conditions, thus enhancing our understanding of human biology and disease mechanisms.
From a scientific standpoint, these cell lines are of paramount importance in both research and clinical settings. They serve as critical tools for drug development, biomarker discovery, and the elucidation of genetic contributions to disease. Researchers can utilize the DISP1 knockout model to uncover potential therapeutic targets or to test novel compounds that may interfere with aberrant signaling associated with DISP1 dysfunction.
Compared to alternative models, the DISP1 Gene Knockout Cell Lines offer unique advantages, including high specificity of gene editing, a streamlined approach to genetic study, and adaptability to various experimental conditions. Their utilization results in robust and reproducible data, making them an essential addition to any laboratory focused on genetic research and therapeutic interventions.
For researchers and clinicians, the value of DISP1 Gene Knockout Cell Lines lies in their ability to provide a focused platform for unraveling the complexities of gene function, ultimately bridging gaps in knowledge that can translate into clinical advancements. Our company has deep expertise in developing high-quality biological products tailored to the needs of the research community. We are committed to supporting scientific innovation and facilitating discoveries that drive progress in health and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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