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DHX29 Knockout Cell Lines

Gene: DHX29

Official Full Name: DExH-box helicase 29provided by HGNC

Gene Summary: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein functions in translation initiation, and is specifically required for ribosomal scanning across stable mRNA secondary structures during initiation codon selection. This protein may also play a role in sensing virally derived cytosolic nucleic acids. Knockdown of this gene results in reduced protein translation and impaired proliferation of cancer cells. [provided by RefSeq, Sep 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21672 DHX29 Knockout cell line (HeLa) Human DHX29 1:3~1:6 Negative Online Inquiry
KO21673 DHX29 Knockout cell line (HCT 116) Human DHX29 1:2~1:4 Negative Online Inquiry
KO21674 DHX29 Knockout cell line (HEK293) Human DHX29 1:3~1:6 Negative Online Inquiry
KO21675 DHX29 Knockout cell line (A549) Human DHX29 1:3~1:4 Negative Online Inquiry

Background

DHX29 Gene Knockout Cell Lines are meticulously engineered cellular models that utilize gene editing technologies to disrupt the expression of the DHX29 gene. The DHX29 gene encodes a member of the DEAD-box protein family, which is involved in various RNA metabolism processes, including RNA splicing, translation initiation, and ribosome biogenesis. By creating knockout cell lines, researchers can study the functional implications of DHX29 loss in cellular contexts, providing insights into its role in cellular homeostasis and disease states.

The key function of DHX29 Gene Knockout Cell Lines lies in their ability to facilitate an in-depth understanding of DHX29's biological activity through loss-of-function studies. This allows scientists to unveil the downstream effects of DHX29 gene disruption on RNA dynamics, cellular growth, differentiation, and signal transduction pathways. Additionally, by utilizing these knockout models, researchers can identify potential biomarkers and therapeutic targets, paving the way for the development of novel treatments and interventions for diseases related to RNA metabolism dysfunction.

The scientific importance of these knockout cell lines is vast, particularly in cancer research and developmental biology, where aberrations in RNA processing often drive pathology. These models enable precise investigations into the role of DHX29 across various conditions, including tumors and genetic disorders, providing critical insights that can inform clinical strategies.

Compared to conventional methods of gene manipulation, DHX29 Gene Knockout Cell Lines offer unparalleled specificity and reliability, ensuring reproducibility of results. Unlike transient silencing techniques, these stable knockout lines maintain consistent gene disruption over extended periods, thereby enhancing experimental viability and depth of study.

For researchers and clinicians alike, DHX29 Gene Knockout Cell Lines represent an indispensable tool in the quest for understanding complex biological systems and identifying novel therapeutic approaches. These products are not only easy to handle but are also supported by our comprehensive cell culture and experimental protocols, ensuring users can maximize the utility of their research endeavors.

Having established a reputation for precision and expertise, our company is committed to providing high-quality biological products that empower scientific discovery and innovation. With ongoing support and expertise, we help researchers navigate the complexities of gene function exploration efficiently and effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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