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DEAF1 Knockout Cell Lines

Gene: DEAF1

Official Full Name: DEAF1 transcription factorprovided by HGNC

Gene Summary: This gene encodes a zinc finger domain-containing protein that functions as a regulator of transcription. The encoded proteins binds to its own promoter as well as to that of several target genes. Activity of this protein is important in the regulation of embryonic development. Mutations in this gene have been found in individuals with autosomal dominant cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31751 DEAF1 Knockout cell line (HeLa) Human DEAF1 1:3~1:6 Negative Online Inquiry
KO31752 DEAF1 Knockout cell line (HCT 116) Human DEAF1 1:2~1:4 Negative Online Inquiry
KO31753 DEAF1 Knockout cell line (HEK293) Human DEAF1 1:3~1:6 Negative Online Inquiry
KO31754 DEAF1 Knockout cell line (A549) Human DEAF1 1:3~1:4 Negative Online Inquiry

Background

DEAF1 Gene Knockout Cell Lines are genetically engineered cells that have had the DEAF1 gene specifically disrupted or "knocked out." This innovative product allows researchers to study the role of DEAF1, a transcription factor implicated in various biological processes, including cell differentiation and response to environmental stimuli. By using these knockout cell lines, scientists can elucidate the functional consequences of DEAF1 loss, enabling them to better understand its involvement in human diseases, particularly neurodevelopmental disorders and certain cancers.

The key function of the DEAF1 Gene Knockout Cell Lines lies in their ability to provide a clear model for examining the gene's role in cellular pathways. The mechanism behind the knockout involves site-specific gene editing techniques, such as CRISPR-Cas9, which ensures precise disruption of the target gene. This creates a controlled experimental setup where the effects of DEAF1 absence can be measured, with implications for cellular behavior, gene expression patterns, and protein interactions.

The scientific importance of DEAF1 Gene Knockout Cell Lines extends beyond basic research; they are vital tools in the development of therapeutic strategies and drug discovery. In clinical settings, understanding the gene's function can guide targeted treatments for conditions linked to DEAF1, making this product invaluable for both academic and industrial research institutions.

When compared to traditional cell lines or non-targeted approaches, our DEAF1 Gene Knockout Cell Lines offer unparalleled precision in studying gene function. This specificity reduces background noise, thereby enhancing the reliability of experimental results. Additionally, their ease of use in various assays, including high-throughput screening and in vivo studies, positions them as a preferred choice among researchers.

Researchers and clinicians will find great value in the DEAF1 Gene Knockout Cell Lines because they facilitate advanced investigations into gene function and regulation. By leveraging these uniquely characterized cell lines, professionals can accelerate their research initiatives while generating high-quality data.

Incorporating years of expertise in genetic engineering and cellular biology, our company is dedicated to providing cutting-edge biological products that drive scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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