Home / DDI2 Knockout Cell Lines

DDI2 Knockout Cell Lines

Gene: DDI2

Official Full Name: DNA damage inducible 1 homolog 2provided by HGNC

Gene Summary: Enables aspartic-type endopeptidase activity; identical protein binding activity; and ubiquitin binding activity. Involved in several processes, including cellular response to hydroxyurea; proteolysis; and regulation of DNA stability. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24951 DDI2 Knockout cell line (HeLa) Human DDI2 1:3~1:6 Negative Online Inquiry
KO24952 DDI2 Knockout cell line (HCT 116) Human DDI2 1:2~1:4 Negative Online Inquiry
KO24953 DDI2 Knockout cell line (HEK293) Human DDI2 1:3~1:6 Negative Online Inquiry
KO24954 DDI2 Knockout cell line (A549) Human DDI2 1:3~1:4 Negative Online Inquiry

Background

DDI2 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to study the functions and implications of the DDI2 gene in various biological processes. These cell lines are created through advanced CRISPR-Cas9 gene editing technology, resulting in precise deletions or inactivations of the DDI2 gene. This manipulation allows researchers to examine the cellular mechanisms and pathway alterations triggered by the absence of DDI2, offering insights into its role in cancer biology, stress response, and other significant physiological phenomena.

The key functions of DDI2 encompass involvement in the regulation of protein degradation and cellular stress responses, notably through the degradation of misfolded proteins. By utilizing these knockout cell lines, investigators can elucidate the downstream effects when DDI2's functions are inhibited, enabling a better understanding of disease mechanisms and potential therapeutic targets.

Scientifically, DDI2 Gene Knockout Cell Lines are invaluable in research and clinical settings, where they can be employed in drug discovery, functional genomics, and the validation of novel therapeutic approaches. The unique ability to dissect the cellular consequences of DDI2 loss contributes to a broader understanding of its implications in various diseases, particularly in oncology and neurodegenerative disorders.

Compared to traditional methods that rely on knockdown approaches or wild-type models, our knockout lines ensure complete gene silence, providing clarity and robustness in experimental data. Their reproducibility and reliability enhance experimental outcomes, setting a gold standard in genetic research.

Researchers and clinicians will find the DDI2 Gene Knockout Cell Lines particularly advantageous due to their thorough characterization, ease of use, and integration into diverse experimental paradigms. As a product of our company’s sustained dedication to innovative biotechnology and extensive experience in genetic engineering, these cell lines stand as a testament to our commitment to providing high-quality tools to advance scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.