Home / DAZAP1 Knockout Cell Lines

DAZAP1 Knockout Cell Lines

Gene: DAZAP1

Official Full Name: DAZ associated protein 1provided by HGNC

Gene Summary: In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05307 DAZAP1 Knockout cell line (HeLa) Human DAZAP1 1:3~1:6 Negative Online Inquiry
KO05308 DAZAP1 Knockout cell line (HCT 116) Human DAZAP1 1:2~1:4 Negative Online Inquiry
KO05309 DAZAP1 Knockout cell line (HEK293) Human DAZAP1 1:3~1:6 Negative Online Inquiry
KO05310 DAZAP1 Knockout cell line (A549) Human DAZAP1 1:3~1:4 Negative Online Inquiry

Background

DAZAP1 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the expression of the DAZAP1 gene, a crucial component in the regulation of mRNA stability and translation. These cell lines serve as invaluable tools for researchers investigating the intricate roles that DAZAP1 plays in various cellular processes, including cell differentiation, stress responses, and signal transduction pathways.

The key functionality of DAZAP1 Gene Knockout Cell Lines lies in their ability to elucidate the mechanistic roles of the DAZAP1 protein by allowing scientists to analyze the resultant phenotypic changes upon its absence. By employing techniques such as RNA sequencing, Western blotting, and quantitative PCR, researchers can quantify alterations in gene expression patterns, protein interactions, and overall cellular behavior, providing insights into the gene's contributions to pathophysiological conditions.

The scientific importance of these cell lines is underscored by their potential applications in both research and clinical settings, particularly in studying diseases where DAZAP1 expression is implicated, such as cancer and neurodegenerative disorders. They enable targeted investigations into therapeutic strategies that could modulate DAZAP1 functions, presenting opportunities for the development of novel treatments.

Compared to alternative systems, such as traditional overexpression assays or full organism models, DAZAP1 Gene Knockout Cell Lines offer a more straightforward, reproducible, and controlled environment for examining specific gene function effects. Moreover, they minimize genetic variability, enhancing the reliability of experimental outcomes.

For researchers and clinicians alike, the value of DAZAP1 Gene Knockout Cell Lines lies not just in their capability to accelerate the understanding of gene functions but also in facilitating the translation of that knowledge into potential therapeutic strategies. With our company's expertise in producing high-quality biological research tools, we are dedicated to supporting your research goals with innovative solutions that expand the frontiers of molecular and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.