Gene: DAW1
Official Full Name: dynein assembly factor with WD repeats 1provided by HGNC
Gene Summary: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in protein polyubiquitination. Predicted to act upstream of with a positive effect on outer dynein arm assembly. Predicted to act upstream of or within with a positive effect on intraciliary transport. Predicted to act upstream of or within several processes, including cerebrospinal fluid circulation; determination of left/right symmetry; and heart development. Predicted to be located in ciliary basal body. Predicted to be part of SCF ubiquitin ligase complex. Implicated in primary ciliary dyskinesia. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18408 | DAW1 Knockout cell line (A549) | Human | DAW1 | 1:3~1:4 | Negative | Online Inquiry |
DAW1 Gene Knockout Cell Lines are specifically engineered cellular models that lack the DAW1 gene, allowing researchers to study the role of this gene in cellular processes and disease mechanisms. These knockout cell lines are created using advanced CRISPR-Cas9 gene editing technology, which enables precise deletion of target genes with minimal off-target effects. The result is a powerful tool for examining the downstream effects of DAW1 disruption on various biological pathways and cellular functions.
The key functions of DAW1 gene knockout cell lines extend beyond merely silencing the gene; they enable the investigation of the gene's involvement in critical processes such as cell proliferation, differentiation, and apoptosis. By leveraging these knockout models, researchers can elucidate the molecular mechanisms by which DAW1 contributes to physiological and pathological states, thereby facilitating a deeper understanding of how alterations in this gene might lead to diseases such as cancer and autoimmune disorders.
The scientific importance of these cell lines is underscored by their broad applications in both basic research and clinical settings. For instance, they can be used to screen for potential drug targets, study gene interactions, and assess the impact of environmental factors on gene expression. Their utility makes them invaluable for researchers focused on genetic research, drug discovery, and biomarker development.
When compared to alternative products, DAW1 Gene Knockout Cell Lines offer several distinct advantages. They have been rigorously validated for specificity and functionality, ensuring reliable experimental outcomes. Additionally, these cell lines are provided with comprehensive user support materials, including detailed experimental protocols and troubleshooting guidance, making them easy to adopt for both novice and experienced researchers alike.
The value of DAW1 Gene Knockout Cell Lines lies in their capability to foster novel insights into gene function and disease pathology, empowering researchers and clinicians to advance their studies and potentially develop targeted therapies. This product aligns with our company’s commitment to providing top-tier biological research tools, backed by a team of experts dedicated to advancing scientific discovery through high-quality offerings.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.