Gene: DAG1
Official Full Name: dystroglycan 1provided by HGNC
Gene Summary: This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. [provided by RefSeq, Nov 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01981 | DAG1 Knockout cell line (HeLa) | Human | DAG1 | 1:3~1:6 | Negative | Online Inquiry |
KO01982 | DAG1 Knockout cell line (HCT 116) | Human | DAG1 | 1:2~1:4 | Negative | Online Inquiry |
KO01983 | DAG1 Knockout cell line (HEK293) | Human | DAG1 | 1:3~1:6 | Negative | Online Inquiry |
KO01984 | DAG1 Knockout cell line (A549) | Human | DAG1 | 1:3~1:4 | Negative | Online Inquiry |
DAG1 Gene Knockout Cell Lines are specialized cell models created to eliminate the expression of the DAG1 gene, which encodes the dystroglycan protein, a crucial component involved in muscle and neuronal cell function. These cell lines are engineered using advanced CRISPR/Cas9 technology, ensuring specific and efficient gene editing, allowing researchers to study the physiological role of DAG1 and its implications in various diseases, including muscular dystrophies and certain cancers.
The key function of DAG1 is its role in cell adhesion and signaling, linking the extracellular matrix to the cytoskeleton of neighboring cells. By knocking out this gene, researchers can investigate the downstream effects on signaling pathways, cellular interactions, and overall cellular architecture. The resulting insights can illuminate pathological processes and help in the development of therapeutic strategies aimed at targeting the dystroglycan pathway.
In both research and clinical settings, DAG1 Gene Knockout Cell Lines hold significant importance. They serve as a robust platform for drug discovery, functional genomics, and pathophysiological studies, enabling scientists to identify potential targets for therapeutic intervention. Moreover, these cell lines facilitate the examination of endogenous repair mechanisms and the cellular response to injury, promoting advancements in regenerative medicine.
A key advantage of our DAG1 Gene Knockout Cell Lines lies in their precision and stability compared to traditional knockout methods, which may not effectively eliminate gene function. Our cutting-edge approach ensures reproducibility and scalability, making these cell lines a valuable resource for ongoing research initiatives.
Researchers, clinicians, and biotechnology companies will find these cell lines essential for elucidating the complexities of DAG1-related biological processes. Their ability to provide a clearer understanding of disease mechanisms offers new avenues for targeted therapies, positioning these models at the forefront of genetic research.
At [Company Name], we bring years of expertise in cell line development and genetic engineering, ensuring that our products meet the rigorous standards required for groundbreaking scientific research. Our commitment to excellence means that we provide not just products, but comprehensive solutions tailored to advance your research goals.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.