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CZIB Knockout Cell Lines

Gene: CZIB

Official Full Name: CXXC motif containing zinc binding proteinprovided by HGNC

Gene Summary: Enables zinc ion binding activity. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18417 CZIB Knockout cell line (HeLa) Human CZIB 1:3~1:6 Negative Online Inquiry
KO18418 CZIB Knockout cell line (HCT 116) Human CZIB 1:2~1:4 Negative Online Inquiry
KO18419 CZIB Knockout cell line (HEK293) Human CZIB 1:3~1:6 Negative Online Inquiry
KO18420 CZIB Knockout cell line (A549) Human CZIB 1:3~1:4 Negative Online Inquiry

Background

CZIB Gene Knockout Cell Lines are a sophisticated biotechnological tool designed for targeted genomic modifications, enabling researchers to gain insights into gene function and associated pathways. Developed through precise CRISPR-Cas9 technology, these cell lines facilitate the study of gene knockout effects in a controlled environment, thereby elucidating the role of specific genes in various biological processes.

The mechanism by which CZIB Gene Knockout Cell Lines operate revolves around the precise alteration of the genomic DNA of host cells. Using a guide RNA that directs the Cas9 nuclease to specific DNA sequences, researchers can effectively introduce double-stranded breaks at target locations. This initiates the cellular repair mechanism, which, when harnessed purposely, leads to the disruption of gene function. The resulting cell lines are invaluable for studying gene expression, cellular responses to environmental stimuli, and the underlying molecular mechanisms of diseases.

In terms of scientific importance, these cell lines are crucial for advancing genetic research, particularly in developmental biology, cancer research, and therapeutic development. They provide a versatile platform for high-throughput screening, drug discovery, and understanding gene-environment interactions. In clinical settings, CZIB Gene Knockout Cell Lines can inform the development of gene-targeted therapies, enhancing precision medicine approaches.

What sets CZIB Gene Knockout Cell Lines apart from alternative products is their high efficiency in gene editing, coupled with extensive validation against off-target effects. Each cell line is characterized for consistency in knockout efficacy, ensuring reliable and reproducible results across experiments. Additionally, our commitment to providing comprehensive support—including detailed protocols, troubleshooting assistance, and application tips—empowers researchers to maximize the utility of these resources in their studies.

For researchers and clinicians aiming to delve deeper into gene functionality, CZIB Gene Knockout Cell Lines represent a valuable asset in their toolkit, enhancing their capacity to make significant contributions to scientific knowledge and therapeutic advancements. With a steadfast dedication to innovation in biological product development, our company stands at the forefront, committed to empowering scientific discovery through tailored and high-quality products.

Please note that all services are for research use only. Not intended for any clinical use.

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