Gene: CYP4F11
Official Full Name: cytochrome P450 family 4 subfamily F member 11provided by HGNC
Gene Summary: This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18450 | CYP4F11 Knockout cell line (HeLa) | Human | CYP4F11 | 1:3~1:6 | Negative | Online Inquiry |
KO18451 | CYP4F11 Knockout cell line (HCT 116) | Human | CYP4F11 | 1:2~1:4 | Negative | Online Inquiry |
KO18452 | CYP4F11 Knockout cell line (A549) | Human | CYP4F11 | 1:3~1:4 | Negative | Online Inquiry |
CYP4F11 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to lack the CYP4F11 gene, which encodes a member of the cytochrome P450 family of enzymes involved in drug metabolism and biosynthesis of various endogenous compounds. This product serves as a powerful tool for researchers interested in unraveling the biochemical pathways influenced by CYP4F11 and understanding its role in pharmacokinetics, toxicology, and disease pathology.
The core function of these knockout cell lines is to facilitate the investigation of CYP4F11’s contributions to lipid metabolism and the metabolism of therapeutic agents. By comparing these knockout models to wild-type counterparts, researchers can elucidate the metabolic processes and mechanistic pathways impacted by the absence of CYP4F11, thereby advancing the understanding of the enzyme's role in diseases such as cancer, cardiovascular disorders, and inflammation.
The scientific importance of CYP4F11 Gene Knockout Cell Lines lies in their versatile applications in both basic and applied research settings. They are invaluable for pharmacological studies aimed at assessing drug interactions and responses, as well as for toxicological assessments that consider the metabolic contributions of the CYP4F11 enzyme. In clinical research, these models can aid in identifying genetic predispositions to adverse drug reactions and tailoring personalized medicinal approaches.
One of the distinct advantages of using CYP4F11 Gene Knockout Cell Lines over other existing models is the precision afforded by gene knockout technology, allowing for targeted investigations without the confounding influences of the gene in question. This specificity can enhance the reliability of experimental outcomes and reduce variability associated with the use of heterogeneous cell populations.
This product is particularly valuable for researchers and clinicians focusing on drug development and therapeutic applications, as it provides insights that can improve drug efficacy and safety profiles. Additionally, it supports a better understanding of individual differences in drug metabolism, promoting advancements in precision medicine.
Our company prides itself on delivering high-quality, rigorously validated biological products that empower research and innovation. With a commitment to scientific excellence, we strive to support the scientific community with cutting-edge solutions that advance the frontiers of knowledge in pharmacology and beyond.
Please note that all services are for research use only. Not intended for any clinical use.
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