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CTDSP2 Knockout Cell Lines

Gene: CTDSP2

Official Full Name: CTD small phosphatase 2provided by HGNC

Gene Summary: Enables RNA polymerase II CTD heptapeptide repeat phosphatase activity. Involved in protein dephosphorylation. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32280 CTDSP2 Knockout cell line (HeLa) Human CTDSP2 1:3~1:6 Negative Online Inquiry
KO32281 CTDSP2 Knockout cell line (HCT 116) Human CTDSP2 1:2~1:4 Negative Online Inquiry
KO32282 CTDSP2 Knockout cell line (HEK293) Human CTDSP2 1:3~1:6 Negative Online Inquiry
KO32283 CTDSP2 Knockout cell line (A549) Human CTDSP2 1:3~1:4 Negative Online Inquiry

Background

CTDSP2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the CTDSP2 gene, providing invaluable tools for studying the gene's role in various biological processes and disease mechanisms. The creation of these knockout cell lines involves the use of targeted CRISPR/Cas9 gene-editing technology, which precisely introduces double-strand breaks at the CTDSP2 locus, leading to the disruption of gene function. By eliminating CTDSP2 expression, researchers can elucidate its involvement in critical pathways such as RNA processing, cell signaling, and stress responses.

The key function of CTDSP2 is its role as a transcriptional co-regulator that modulates gene expression by interacting with various factors involved in RNA metabolism. This regulatory capacity has significant implications in both basic biological research and translational medicine, as CTDSP2 has been linked to cellular processes such as differentiation, proliferation, and apoptosis. The study of its knockout models allows scientists to better understand how aberrations in this gene may contribute to diseases, including cancer and neurodegenerative disorders.

One of the primary advantages of utilizing CTDSP2 Gene Knockout Cell Lines is their specificity and reliability when investigating gene function, compared to alternative methods like RNA interference, which can produce off-target effects. Furthermore, these cells are well-characterized and can be adapted to various experimental conditions, making them incredibly versatile in both in vitro studies and therapeutic development.

This product is particularly valuable to researchers focused on gene regulation, signaling pathways, and chronic diseases, providing them with a robust platform to develop hypotheses and test novel therapeutic strategies. In clinical settings, understanding the functional consequences of CTDSP2 loss can lead to advancements in personalized medicine approaches for patients with gene-related conditions.

Our company specializes in providing high-quality genetic models that are thoroughly validated, ensuring that researchers have access to reliable tools that will enhance their work. With a commitment to scientific excellence, we strive to support the scientific community in uncovering the complexities of gene function and its implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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