Gene: CSAD
Official Full Name: cysteine sulfinic acid decarboxylaseprovided by HGNC
Gene Summary: This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04844 | CSAD Knockout cell line (HeLa) | Human | CSAD | 1:3~1:6 | Negative | Online Inquiry |
KO04845 | CSAD Knockout cell line (HCT 116) | Human | CSAD | 1:2~1:4 | Negative | Online Inquiry |
KO04846 | CSAD Knockout cell line (HEK293) | Human | CSAD | 1:3~1:6 | Negative | Online Inquiry |
KO04847 | CSAD Knockout cell line (A549) | Human | CSAD | 1:3~1:4 | Negative | Online Inquiry |
CSAD Gene Knockout Cell Lines are specially engineered cellular models designed to study the biological functions of the cysteine sulfinic acid decarboxylase (CSAD) gene. By employing the CRISPR-Cas9 gene-editing technology, these cell lines exhibit a complete knockout of the CSAD gene, enabling researchers to examine the physiological and molecular repercussions of its absence. The CSAD gene is critical in the metabolism of cysteine, influencing various pathways that regulate oxidative stress and cellular signaling.
The primary mechanism of these knockout cell lines lies in their ability to facilitate the research of metabolic disorders and neurodegenerative conditions that are linked to dysregulation of cysteine metabolism. By providing a functional contrast to wild-type cells, scientists can analyze changes in cellular processes, enzyme activity, and gene expression profiles attributable to the loss of CSAD activity. This utility becomes especially pertinent in exploring potential therapeutic approaches that could target these metabolic pathways in diseases.
In both research and clinical applications, the CSAD Gene Knockout Cell Lines hold immense scientific value, allowing for high-throughput screening of drug candidates and the assessment of new therapeutic modalities. Compared to alternative models, such as transient knock-downs or wild-type cells, these stable knockout lines ensure consistently reproducible results, thereby enhancing experimental reliability.
The advantages of utilizing CSAD Gene Knockout Cell Lines extend to their role in elucidating underlying disease mechanisms, testing pharmacological interventions, and advancing our understanding of cellular resilience to oxidative stress. For researchers and clinicians looking to make significant advancements in the field of molecular biology, this product provides pivotal insights that can shape future investigations and therapeutic strategies.
As an established leader in producing high-quality biological products, our company is committed to supporting the scientific community with innovative tools such as CSAD Gene Knockout Cell Lines. We pride ourselves on delivering rigorous, validated, and user-friendly products that facilitate groundbreaking research and the development of novel therapies.
Please note that all services are for research use only. Not intended for any clinical use.
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