Gene: CRIM1
Official Full Name: cysteine rich transmembrane BMP regulator 1provided by HGNC
Gene Summary: This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05601 | CRIM1 Knockout cell line (HeLa) | Human | CRIM1 | 1:3~1:6 | Negative | Online Inquiry |
KO05602 | CRIM1 Knockout cell line (HCT 116) | Human | CRIM1 | 1:2~1:4 | Negative | Online Inquiry |
KO05603 | CRIM1 Knockout cell line (HEK293) | Human | CRIM1 | 1:3~1:6 | Negative | Online Inquiry |
KO05604 | CRIM1 Knockout cell line (A549) | Human | CRIM1 | 1:3~1:4 | Negative | Online Inquiry |
CRIM1 Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the in-depth study of CRIM1 (cysteine-rich motor neuron 1), a gene involved in critical signaling pathways regulating cell adhesion and differentiation in various biological processes. These knockout cell lines have been meticulously developed using CRISPR-Cas9 technology to disrupt the CRIM1 gene, enabling researchers to investigate the absence of CRIM1's functional roles and elucidate its implications in developmental biology, neurobiology, and potential pathology.
The primary function of these cell lines lies in their ability to provide a controlled environment in which researchers can observe changes in cellular behavior, phenotype, and signaling cascades resulting from the loss of CRIM1 expression. This offers insights into cellular response mechanisms, allowing for the identification of novel therapeutic targets in diseases related to neurodevelopmental disorders and cancer progression, where CRIM1 has been implicated. The precise gene knockout ensures reproducibility and reliability, essential qualities for advancing contemporary biomedical research.
In scientific and clinical settings, CRIM1 Gene Knockout Cell Lines are invaluable, aiding in the creation of predictive models that can lead to better understanding and potential treatments for diseases. Their use in drug screening and validation of therapeutic candidates underlines their significance in translational medicine.
What sets our CRIM1 Gene Knockout Cell Lines apart is the stringent quality controls employed throughout the development process, including thorough genotyping and functional validation to ensure integrity and performance. Unlike alternative cell lines, which may provide limited insights due to residual gene expression or variability, our knockout cell lines deliver enhanced clarity in experimental outcomes, making them the optimal choice for discerning the role of CRIM1 in various biological contexts.
The value of our product extends beyond mere research; it encapsulates our commitment to empowering researchers and clinicians with robust tools to drive forward biomedical discoveries. Our extensive experience in genetic engineering and cell line development ensures that these knockout models are developed and distributed with the highest standards of quality and innovation. By choosing our CRIM1 Gene Knockout Cell Lines, users are positioning themselves at the forefront of scientific exploration within their fields.
Please note that all services are for research use only. Not intended for any clinical use.
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