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COPZ2 Knockout Cell Lines

Gene: COPZ2

Official Full Name: COPI coat complex subunit zeta 2provided by HGNC

Gene Summary: This gene encodes a member of the adaptor complexes small subunit family. The encoded protein is a subunit of the coatomer protein complex, a seven-subunit complex that functions in the formation of COPI-type, non-clathrin-coated vesicles. COPI vesicles function in the retrograde Golgi-to-ER transport of dilysine-tagged proteins. [provided by RefSeq, Feb 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22840 COPZ2 Knockout cell line (HeLa) Human COPZ2 1:3~1:6 Negative Online Inquiry
KO22841 COPZ2 Knockout cell line (A549) Human COPZ2 1:3~1:4 Negative Online Inquiry

Background

COPZ2 Gene Knockout Cell Lines are specialized cellular models that have been meticulously developed to facilitate the study of the COPZ2 gene's function by effectively silencing its expression. These cell lines are engineered using advanced CRISPR/Cas9 technology, which introduces targeted mutations in the COPZ2 gene, leading to a complete loss of its protein product. This gene is known to be involved in several critical cellular processes, such as vesicular transport, signal transduction, and cytoskeletal organization. By utilizing COPZ2 gene knockout cell lines, researchers can delve into the role of COPZ2 in various physiological and pathological conditions, illuminating its contributions to diseases such as cancer and neurodegenerative disorders.

The primary function of these knockout cell lines lies in their ability to serve as a powerful tool for examining the gene's impact on cellular behaviors, including growth, differentiation, and response to stimuli. Researchers can compare the knockout cells to wild-type controls to elucidate the specific pathways governed by COPZ2, paving the way for novel therapeutic insights. These cell lines are particularly valuable in drug screening and developmental biology, where understanding gene functions can direct innovative treatment approaches.

What sets COPZ2 Gene Knockout Cell Lines apart from other similar products is the precision and reliability of the CRISPR/Cas9 modification, which minimizes off-target effects and ensures that the knockout is both stable and reproducible. Additionally, the availability of these specific cell lines accelerates research timelines, allowing for rapid experimental turnaround and more robust findings.

For researchers and clinicians, the ability to manipulate COPZ2 expression opens avenues for cutting-edge research, facilitating advancements in both basic biology and clinical applications. By comprehensively analyzing gene knockouts, one can potentially uncover previously unidentified mechanisms of disease or targetable pathways for therapeutics.

Our company is committed to providing high-quality biological research tools backed by extensive expertise in genetic engineering and cellular biology, ensuring that our products meet the rigorous demands of modern scientific inquiry. With our COPZ2 Gene Knockout Cell Lines, researchers are equipped to make significant contributions to the understanding of gene function and its implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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