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COLEC12 Knockout Cell Lines

Gene: COLEC12

Official Full Name: collectin subfamily member 12provided by HGNC

Gene Summary: This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells. [provided by RefSeq, May 2018]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04835 COLEC12 Knockout cell line (HEK293) Human COLEC12 1:3~1:6 Negative Online Inquiry

Background

COLEC12 Gene Knockout Cell Lines are specifically engineered models that enable researchers to study the role of the COLEC12 gene, known to be involved in immunity and inflammatory responses. These cell lines are generated using advanced CRISPR-Cas9 genome editing technology, which allows for precise modification of the gene of interest, resulting in the complete loss of COLEC12 function. By creating a knockout model, researchers can effectively elucidate the biological pathways and mechanisms that COLEC12 influences in various physiological and pathological contexts.

The key function of COLEC12 is its role in the recognition and binding of certain glycoproteins, which are vital for immune response modulation. The knockout cell lines enable scientists to investigate how the absence of COLEC12 impacts cellular behavior, signaling pathways, and interaction with pathogens. Such insights are critical for understanding autoimmune diseases, infections, and potential therapeutic interventions.

The scientific importance of COLEC12 Gene Knockout Cell Lines lies in their broad applicability within both research and clinical settings. These cell lines provide a robust platform for drug discovery, functional studies, and the development of targeted therapies, facilitating breakthroughs in understanding complex immune disorders.

What sets our COLEC12 Gene Knockout Cell Lines apart from alternative models is their validated genetic modification, high reproducibility, and the availability of supporting data for experimental use. Our cell lines come with comprehensive validation protocols, ensuring reliability and consistency in experimental outcomes, which is paramount for rigorous scientific research.

For researchers and clinicians, investing in COLEC12 Gene Knockout Cell Lines translates to a powerful tool that accelerates the understanding of immune mechanisms and the development of innovative therapies. With our expertise in biological products and a commitment to quality, we provide not only cell lines but also exceptional customer support and scientific resources to enhance your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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