Gene: CNTN1
Official Full Name: contactin 1provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38491 | CNTN1 Knockout cell line (HCT 116) | Human | CNTN1 | 1:2~1:4 | Negative | Online Inquiry |
KO38492 | CNTN1 Knockout cell line (HEK293) | Human | CNTN1 | 1:3~1:6 | Negative | Online Inquiry |
KO38493 | CNTN1 Knockout cell line (A549) | Human | CNTN1 | 1:3~1:4 | Negative | Online Inquiry |
CNTN1 Gene Knockout Cell Lines are specially engineered cell lines designed to facilitate the study of contactin 1 (CNTN1), a cell adhesion molecule implicated in various neurological processes and disorders. These knockout models enable researchers to investigate the role of CNTN1 in neuronal development, synaptic plasticity, and disease mechanisms, including multiple sclerosis, autism, and other neurodegenerative conditions. By specifically targeting and disrupting the CNTN1 gene, these cell lines provide unique insights into how alterations in this molecule affect cellular signaling and interactions.
The mechanism driving the functionality of CNTN1 Gene Knockout Cell Lines lies in the targeted gene editing techniques employed, such as CRISPR/Cas9, which effectively eliminate the expression of CNTN1 without off-target effects. This enables a comparison of phenotypic and functional characteristics between knockout and wild-type cells, thereby allowing for the elucidation of CNTN1's specific roles in cellular pathways and neurobiology.
From a scientific perspective, these knockout cell lines are invaluable tools for academic and clinical researchers, providing a controlled environment to model human diseases at the cellular level. They serve as platforms for therapeutic testing and the evaluation of pharmacological agents, paving the way for the development of novel treatment strategies.
Compared to traditional methods of studying gene function, CNTN1 Gene Knockout Cell Lines uniquely offer a more precise approach through defined genetic alterations, significantly improving reproducibility and reliability of experimental results. Additionally, the availability of these cell lines can reduce research timelines and costs associated with generating knockout models from scratch.
For researchers and clinicians focused on neurobiology and related fields, CNTN1 Gene Knockout Cell Lines represent a significant advancement in understanding the complexities of neuronal function and disorders. Our company specializes in the production of high-quality, validated cell lines, ensuring that our customers have access to state-of-the-art tools essential for cutting-edge research and clinical applications in the biological sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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