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CNOT6L Knockout Cell Lines

Gene: CNOT6L

Official Full Name: CCR4-NOT transcription complex subunit 6 likeprovided by HGNC

Gene Summary: Predicted to enable poly(A)-specific ribonuclease activity. Involved in positive regulation of cell population proliferation and positive regulation of cytoplasmic mRNA processing body assembly. Located in cytosol and nucleus. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21504 CNOT6L Knockout cell line (HeLa) Human CNOT6L 1:3~1:6 Negative Online Inquiry
KO21505 CNOT6L Knockout cell line (HCT 116) Human CNOT6L 1:2~1:4 Negative Online Inquiry
KO21506 CNOT6L Knockout cell line (HEK293) Human CNOT6L 1:3~1:6 Negative Online Inquiry
KO21507 CNOT6L Knockout cell line (A549) Human CNOT6L 1:3~1:4 Negative Online Inquiry

Background

CNOT6L Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed for studying gene function and regulation. These cell lines are engineered to lack the CNOT6L gene, an integral component of the CCR4-NOT complex, which is involved in mRNA turnover and gene expression modulation. By utilizing CRISPR-Cas9 or similar genome-editing technologies, researchers can effectively observe the biological implications of the loss of CNOT6L activity, providing insights into its role in cellular processes such as proliferation, differentiation, and response to stressors.

The key functions of these knockout cell lines allow scientists to delve deeper into the molecular mechanisms underlying gene regulation, offering a unique platform to analyze the effects of CNOT6L absence on RNA metabolism and protein synthesis. This enables a clearer understanding of various diseases, including cancer, where dysregulation of mRNA dynamics plays a significant role. Furthermore, these cell lines facilitate the exploration of potential therapeutic targets that could aid in drug discovery processes.

The scientific importance of CNOT6L knockout cell lines extends to numerous research and clinical applications, from basic research elucidating gene function to translational studies aiming to combat diseases linked to mRNA regulation. Researchers looking to investigate gene interactions and signaling pathways can significantly benefit from these lines as they offer a reliable and standardized background, reducing variability seen with heterogeneous cell populations.

What sets CNOT6L Gene Knockout Cell Lines apart from traditional models is their precision and reproducibility. Unlike alternative methods that can yield inconsistent results, these knockout lines provide a stable and uniform genetic background, ensuring that findings are attributable solely to the absence of the CNOT6L gene. This enhances credibility and boosts the impact of scientific outputs.

For researchers and clinicians committed to advancing our understanding of gene regulation and its implications for health and disease, CNOT6L Gene Knockout Cell Lines serve as an invaluable resource. Their ability to streamline innovative research projects and improve reproducibility makes them a pivotal component in the toolkit of modern molecular biology.

Our company brings extensive expertise in cell line development and genetic engineering, ensuring that our products meet the highest standards of scientific rigor and reliability. By choosing our CNOT6L Gene Knockout Cell Lines, you are partnering with a leader in the field, dedicated to supporting your research endeavors with top-tier biological products.

Please note that all services are for research use only. Not intended for any clinical use.

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