Gene: CNN2
Official Full Name: calponin 2provided by HGNC
Gene Summary: The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38494 | CNN2 Knockout cell line (HeLa) | Human | CNN2 | 1:3~1:6 | Negative | Online Inquiry |
KO38495 | CNN2 Knockout cell line (HCT 116) | Human | CNN2 | 1:2~1:4 | Negative | Online Inquiry |
KO38496 | CNN2 Knockout cell line (HEK293) | Human | CNN2 | 1:3~1:6 | Negative | Online Inquiry |
KO38497 | CNN2 Knockout cell line (A549) | Human | CNN2 | 1:3~1:4 | Negative | Online Inquiry |
CNN2 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to lack the expression of the CNN2 gene, also known as Calponin 2. This innovative product serves as a tool for investigating the functional roles of CNN2 in various biological processes, including cell contraction, motility, and differentiation. By utilizing CRISPR-Cas9 gene editing technology, these cell lines offer robust models for researchers aiming to explore the implications of CNN2 dysregulation in health and disease.
The key functionality of these cell lines stems from their ability to enable researchers to dissect the pathways and molecular mechanisms influenced by the absence of CNN2. By studying the alterations in gene expression, signaling pathways, and cellular behavior, researchers can gain insights into the contributions of CNN2 to diseases such as cancer and cardiovascular disorders. This is particularly valuable in areas such as regenerative medicine and developmental biology, where understanding these cellular dynamics is essential.
In terms of scientific significance, CNN2 Gene Knockout Cell Lines provide a vital model for research that could lead to novel therapeutic strategies. Their applications extend to drug discovery, where the response of CNN2-null cells to various compounds can shed light on potential treatment options. Furthermore, these cell lines enhance our understanding of gene interaction networks, making them relevant for researchers looking to elucidate complex biological systems.
Compared to alternative models, CNN2 Gene Knockout Cell Lines offer the advantage of precise gene editing without the confounding effects often associated with traditional knockout models. As a purer system, they reduce background noise, allowing for clearer interpretation of experimental outcomes. Moreover, the customization capabilities of these cell lines enable users to generate specific, tailored research findings that can lead to groundbreaking advancements.
For researchers and clinicians seeking to delve into the multifaceted roles of CNN2, these knockout cell lines represent an invaluable asset, providing a clear path to deeper biological understanding and potential clinical translation. Our commitment to excellence in genetic engineering ensures that our product meets the highest standards, backed by our dedicated team's expertise in developing innovative biological tools. By choosing CNN2 Gene Knockout Cell Lines, users invest in high-quality research solutions that pave the way for future discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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