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CLYBL Knockout Cell Lines

Gene: CLYBL

Official Full Name: citramalyl-CoA lyaseprovided by HGNC

Gene Summary: Enables (S)-citramalyl-CoA lyase activity; magnesium ion binding activity; and malate synthase activity. Involved in protein homotrimerization and regulation of cobalamin metabolic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18654 CLYBL Knockout cell line (HeLa) Human CLYBL 1:3~1:6 Negative Online Inquiry
KO18655 CLYBL Knockout cell line (HCT 116) Human CLYBL 1:2~1:4 Negative Online Inquiry
KO18656 CLYBL Knockout cell line (HEK293) Human CLYBL 1:3~1:6 Negative Online Inquiry
KO18657 CLYBL Knockout cell line (A549) Human CLYBL 1:3~1:4 Negative Online Inquiry

Background

CLYBL Gene Knockout Cell Lines are advanced human cell line models developed to specifically investigate the function of the CLYBL gene and its implicative role in various biological processes and disease mechanisms. These engineered cell lines are created through CRISPR/Cas9 technology, enabling precise gene editing that results in reliable, reproducible knockout phenotypes. By suppressing the expression of CLYBL, researchers can elucidate its biological functions, assess its contribution to metabolic pathways, and evaluate potential therapeutic targets in diseases where CLYBL may play a critical role.

The key mechanism underlying CLYBL Gene Knockout Cell Lines relies on the strategic interruption of the CLYBL gene, leading to the absence of its encoded protein. This knockout approach allows scientists to conduct functional assays, analyze downstream signaling pathways, and observe phenotypic changes that arise due to the loss of gene expression. Such insights can be vital in understanding pathological conditions and refining therapeutic strategies aimed at diseases such as cancer and metabolic disorders.

CLYBL Gene Knockout Cell Lines stand out for their high specificity and accuracy compared to traditional methods of gene disruption, such as siRNA or antisense oligonucleotides, which may lead to off-target effects or incomplete gene silencing. Additionally, these cell lines are invaluable not only in basic research but also in drug development and preclinical studies, providing a robust platform for testing drug efficacy and safety.

For researchers and clinicians, the availability of CLYBL Gene Knockout Cell Lines represents a significant opportunity to advance knowledge in gene function and regulation, facilitating breakthroughs in personalized medicine and targeted therapies. Our company brings years of expertise in genetic engineering and cell line development, offering high-quality products that meet rigorous scientific standards to assist the scientific community in their pursuit of innovative research solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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