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CIZ1 Knockout Cell Lines

Gene: CIZ1

Official Full Name: CDKN1A interacting zinc finger protein 1provided by HGNC

Gene Summary: The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28828 CIZ1 Knockout cell line (HeLa) Human CIZ1 1:3~1:6 Negative Online Inquiry
KO28829 CIZ1 Knockout cell line (HCT 116) Human CIZ1 1:2~1:4 Negative Online Inquiry
KO28830 CIZ1 Knockout cell line (HEK293) Human CIZ1 1:3~1:6 Negative Online Inquiry
KO28831 CIZ1 Knockout cell line (A549) Human CIZ1 1:3~1:4 Negative Online Inquiry

Background

CIZ1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the CIZ1 (CDK2 interacting zinc finger protein 1) gene, a crucial player in the regulation of DNA replication and cellular proliferation. The CIZ1 protein is known for its role in genomic stability and its involvement in oncogenic processes. By providing a means to study the direct effects of CIZ1 deficiency, these knockout cell lines serve as powerful tools for examining the biological functions associated with this protein and its implications in cancer pathology and developmental biology.

The functionality of CIZ1 Gene Knockout Cell Lines resides in their ability to eliminate the confounding variables present in wild-type cells. Researchers can utilize these cell lines to investigate the downstream effects of CIZ1 loss, such as alterations in cell cycle progression, DNA repair mechanisms, and tumorigenesis. This allows for the dissection of mechanistic pathways and contributes to a more sophisticated understanding of how CIZ1 impacts cellular behavior.

In terms of scientific importance, these cell lines are invaluable for cancer research, as they facilitate the exploration of therapeutic targets and mechanisms of drug resistance associated with CIZ1 dysregulation. Furthermore, they have applications in genetic studies assessing the role of CIZ1 in cell growth and differentiation, making them relevant tools across diverse fields such as oncology and developmental biology.

Compared to traditional cell lines, CIZ1 Gene Knockout Cell Lines offer unique advantages, including a more defined genetic background and the ability to conduct focused functional assays. This specificity enhances result reproducibility and reliability compared to the use of diverse heterogeneous populations of cells.

For researchers and clinicians seeking to deepen their understanding of cell biology and cancer mechanisms, CIZ1 Gene Knockout Cell Lines present a high-value resource that supports innovative experimentation and discovery. The precision and reliability of these cell lines transform them into essential components for cutting-edge research.

Our company is dedicated to providing high-quality biological products that meet the evolving needs of the scientific community. With a commitment to excellence and innovation, we ensure that every product, including our CIZ1 Gene Knockout Cell Lines, embodies the highest standards of reliability and performance that researchers can trust for their critical studies.

Please note that all services are for research use only. Not intended for any clinical use.

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