Gene: CISD2
Official Full Name: CDGSH iron sulfur domain 2provided by HGNC
Gene Summary: The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20928 | CISD2 Knockout cell line (HeLa) | Human | CISD2 | 1:3~1:6 | Negative | Online Inquiry |
KO20929 | CISD2 Knockout cell line (HCT 116) | Human | CISD2 | 1:2~1:4 | Negative | Online Inquiry |
KO20930 | CISD2 Knockout cell line (HEK293) | Human | CISD2 | 1:3~1:6 | Negative | Online Inquiry |
KO20931 | CISD2 Knockout cell line (A549) | Human | CISD2 | 1:3~1:4 | Negative | Online Inquiry |
CISD2 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the expression of the CISD2 gene, which encodes a protein associated with mitochondrial function and calcium homeostasis. These knockout models serve as a crucial tool for understanding the role of CISD2 in various cellular processes, including oxidative stress response, apoptosis, and metabolic regulation.
The primary function of these cell lines involves the elucidation of cellular mechanisms impacted by the absence of CISD2. Researchers can investigate the resultant alterations in mitochondrial dynamics, calcium signaling, and cellular metabolism. By utilizing these knockout models, scientists can delineate the pathways affected by CISD2 and assess its implications in diseases such as cancer, neurodegeneration, and metabolic disorders.
The scientific importance of CISD2 Gene Knockout Cell Lines extends into both fundamental research and clinical applications. In research settings, these cell lines enable targeted studies on the gene’s role in pathogenic processes, thereby facilitating the identification of potential therapeutic targets. Clinically, understanding the mechanisms through which CISD2 influences disease progression can inform the development of novel strategies for intervention.
One significant advantage of using CISD2 Gene Knockout Cell Lines is their specificity. Unlike alternative models that may exhibit off-target effects, these lines provide a clean genetic background that allows for clearer interpretations of experimental outcomes. This specificity not only enhances data reliability but also reduces the time and resources spent on validating results.
Moreover, researchers and clinicians will find value in these cell lines due to their potential to accelerate drug discovery and therapeutic development processes. The insights gained from workflows utilizing CISD2 knockout models can lead to breakthroughs in understanding disease aetiology and to the advancement of personalized medicine approaches.
Our company specializes in the development and supply of high-quality, genetically modified cell lines, leveraging years of expertise and a commitment to scientific innovation. By providing reliable biological products like the CISD2 Gene Knockout Cell Lines, we empower researchers and clinicians to push the boundaries of knowledge and therapeutic possibilities.
Please note that all services are for research use only. Not intended for any clinical use.
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