Gene: CHST7
Official Full Name: carbohydrate sulfotransferase 7provided by HGNC
Gene Summary: This gene is a member of the Gal/GalNAc/GlcNAc (galactose/N-acetylgalactosamine/N-acetylglucosamine) 6-O-sulfotransferase (GST) family. Members of this family encode enzymes that catalyze the specific addition of sulfate groups to distinct hydroxyl and amino groups of carbohydrates. The encoded protein catalyzes the sulfation of 6-hydroxyl group of GalNAc in chondroitin. [provided by RefSeq, Aug 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18704 | CHST7 Knockout cell line (HeLa) | Human | CHST7 | 1:3~1:6 | Negative | Online Inquiry |
KO18705 | CHST7 Knockout cell line (HCT 116) | Human | CHST7 | 1:2~1:4 | Negative | Online Inquiry |
KO18706 | CHST7 Knockout cell line (HEK293) | Human | CHST7 | 1:3~1:6 | Negative | Online Inquiry |
KO18707 | CHST7 Knockout cell line (A549) | Human | CHST7 | 1:3~1:4 | Negative | Online Inquiry |
CHST7 Gene Knockout Cell Lines are genetically engineered cell lines designed to allow researchers to study the functional implications of the CHST7 gene, which encodes a sulfotransferase involved in glycosaminoglycan biosynthesis. This product provides a powerful tool for investigating the role of CHST7 in various biological processes, including cell signaling, extracellular matrix formation, and tissue development. By utilizing CRISPR-Cas9 technology, these knockout cell lines exhibit a complete absence of CHST7 function, enabling precise analyses of the gene's contributions to cellular behavior and disease pathology.
The key mechanism of action revolves around the targeted disruption of the CHST7 gene, which results in the loss of its protein product. This knockout serves as an effective model to elucidate the molecular pathways influenced by CHST7, helping scientists uncover its potential implications in cancer biology, developmental disorders, and metabolic syndromes. Such insights are critical not only for basic biological research but also for the development of targeted therapeutic strategies.
The scientific importance of CHST7 Gene Knockout Cell Lines lies in their application in both research and clinical settings. These cell lines provide an innovative platform for drug discovery, facilitating the identification of new therapeutic targets and accelerating the validation of hypotheses related to CHST7's role in health and disease. They enable researchers to perform high-throughput screening, assess drug efficacy, and study gene-environment interactions more effectively.
Compared to traditional knockout models, these cell lines offer several advantages, including faster generation times, more reproducible results, and simplified experimental protocols. This reduces variability and enhances the robustness of experimental outcomes, making them an attractive option for both academic and clinical laboratories.
For researchers and clinicians alike, the CHST7 Gene Knockout Cell Lines are invaluable for their capacity to deepen our understanding of gene function in the context of specialized diseases, which is essential for advancing medical research and therapeutic development. Our company is committed to delivering high-quality biological products backed by cutting-edge technology and expertise in genetic engineering, ensuring that our customers have access to the best tools for their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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