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CFAP43 Knockout Cell Lines

Gene: CFAP43

Official Full Name: cilia and flagella associated protein 43provided by HGNC

Gene Summary: This gene encodes a member of the cilia- and flagella-associated protein family. [provided by RefSeq, Sep 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26120 CFAP43 Knockout cell line (HCT 116) Human CFAP43 1:2~1:4 Negative Online Inquiry
KO26121 CFAP43 Knockout cell line (HEK293) Human CFAP43 1:3~1:6 Negative Online Inquiry

Background

CFAP43 Gene Knockout Cell Lines are genetically engineered cell lines in which the CFAP43 gene has been disrupted or removed. CFAP43, or cilia and flagella associated protein 43, plays a vital role in cellular processes related to ciliary function and motility, making these knockout models invaluable for understanding the biological impacts of its loss. These cell lines allow researchers to study the gene’s function by evaluating the phenotypic consequences associated with its absence, particularly in the context of cellular signaling pathways that govern motility and sensory functions.

The key mechanism underlying the functionality of CFAP43 Gene Knockout Cell Lines lies in the complete or partial disruption of normal CFAP43 protein expression, which may result in defects in ciliary structure and function. By utilizing these cell lines, researchers can investigate how disruptions in ciliary function contribute to various diseases, including ciliopathies, which are a diverse group of genetic disorders caused by dysfunctional cilia.

The scientific importance of these knockout cell lines is underscored by their wide-ranging applications in research settings, particularly in studies focused on developmental biology, cellular signaling, and genetic diseases. The CFAP43 gene's involvement in intricate biological processes makes these cell lines particularly suitable for drug discovery, gene therapy research, and the potential development of therapeutic strategies aimed at restoring normal ciliary function.

Compared to alternative models, such as wild-type cell lines or more general gene knockout technologies, CFAP43 Gene Knockout Cell Lines offer superior specificity and functional insight into ciliary biology. Their precise genomic editing ensures that researchers can rely on the fidelity and reproducibility of results drawn from experiments.

For researchers and clinicians alike, the usability of CFAP43 Gene Knockout Cell Lines in elucidating complex biological mechanisms and the potential for therapeutic intervention render them a crucial tool in modern biomedical research. Our company has a longstanding commitment to developing high-quality biological products, ensuring that scientists have access to accurate and reliable tools for their experimental needs, contributing meaningfully to advancing the frontiers of science.

Please note that all services are for research use only. Not intended for any clinical use.

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