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CEP70 Knockout Cell Lines

Gene: CEP70

Official Full Name: centrosomal protein 70provided by HGNC

Gene Summary: Enables identical protein binding activity. Predicted to be involved in cilium assembly. Located in centrosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26015 CEP70 Knockout cell line (HeLa) Human CEP70 1:3~1:6 Negative Online Inquiry
KO26016 CEP70 Knockout cell line (HCT 116) Human CEP70 1:2~1:4 Negative Online Inquiry
KO26017 CEP70 Knockout cell line (HEK293) Human CEP70 1:3~1:6 Negative Online Inquiry
KO26018 CEP70 Knockout cell line (A549) Human CEP70 1:3~1:4 Negative Online Inquiry

Background

CEP70 Gene Knockout Cell Lines are a sophisticated tool designed to facilitate the study of the CEP70 gene, known for its role in centrosome function and cellular division. These cell lines are engineered to lack the expression of the CEP70 gene, allowing researchers to explore the gene's contributions to various biological processes. By providing a stable platform for genetic manipulation, these knockout cell lines enable in-depth analysis of CEP70's functions in cellular signaling, response to stress, and its implications in oncogenesis.

The primary mechanism of action involves the disruption of the CEP70 gene, leading to alterations in centrosome dynamics and ultimately affecting the cell cycle. Researchers can observe changes in cell morphology, proliferation rates, and response to microtubule-targeting agents such as taxanes or alkaloids. This capacity to investigate the phenotypic consequences of gene knockout forms a critical frontier in understanding the molecular mechanisms underlying diseases, particularly cancer and developmental disorders.

The scientific importance of CEP70 Gene Knockout Cell Lines extends to both research and clinical applications. In research, these models provide insights into fundamental cellular processes, aid in drug discovery efforts, and serve as experimental platforms to test therapeutic strategies targeting centrosome-related pathologies. Clinically, they have the potential to assist in the identification of biomarkers for disease prognosis and treatment response.

What sets our CEP70 Gene Knockout Cell Lines apart from alternative genetic models is their high specificity, validated performance, and reproducible results across multiple experiments. Researchers benefit from the assurance that their findings are drawn from a rigorously characterized system, thereby enhancing the reliability of their conclusions.

In essence, these cell lines offer a powerful and valuable resource for researchers and clinicians alike, supporting investigations that can lead to groundbreaking advances in the understanding and treatment of diseases tied to the CEP70 gene. Our company brings years of expertise in providing high-quality biological products that empower scientific discovery, and we remain committed to advancing research initiatives with innovative solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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