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CEBPD Knockout Cell Lines

Gene: CEBPD

Official Full Name: CCAAT enhancer binding protein deltaprovided by HGNC

Gene Summary: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03589 CEBPD Knockout cell line (HeLa) Human CEBPD 1:3~1:6 Negative Online Inquiry
KO03590 CEBPD Knockout cell line (HCT 116) Human CEBPD 1:2~1:4 Negative Online Inquiry
KO03591 CEBPD Knockout cell line (HEK293) Human CEBPD 1:3~1:6 Negative Online Inquiry
KO03592 CEBPD Knockout cell line (A549) Human CEBPD 1:3~1:4 Negative Online Inquiry

Background

CEBPD Gene Knockout Cell Lines are specialized cellular models created through the targeted disruption of the CCAAT/enhancer-binding protein delta (CEBPD) gene. This gene plays a crucial role in regulating various biological processes, including cell differentiation, metabolism, and immune responses. By knocking out CEBPD expression, researchers gain insights into its functional contributions to cellular phenotypes, providing a valuable tool for studying gene function and regulatory networks.

These cell lines operate through a loss-of-function approach, utilizing CRISPR-Cas9 technology to introduce precise mutations that render the CEBPD gene inactive. As a result, researchers can observe the phenotypic changes and signaling pathways affected by the absence of CEBPD, leading to a deeper understanding of its involvement in pathophysiological conditions such as cancer and metabolic diseases.

The scientific importance of CEBPD Gene Knockout Cell Lines is significant, particularly in the context of research and clinical applications. They serve as an essential tool for drug discovery, toxicity testing, and biomarker identification, enabling the development of therapeutics aimed at modulating CEBPD-related pathways. Furthermore, these cell lines can facilitate the elucidation of CEBPD's role in various diseases, providing critical insights that contribute to personalized medicine approaches.

What distinguishes our CEBPD Gene Knockout Cell Lines from alternatives is the rigor of our customization and validation processes. Our products are derived from extensively characterized parental cell lines, ensuring robustness and reproducibility in experimental outcomes. Additionally, these knockout cell lines come with detailed documentation, including genotyping results and comparative studies, which enhance the reliability of your research.

Researchers, clinicians, and biopharmaceutical professionals will find CEBPD Gene Knockout Cell Lines invaluable for advancing their work. By leveraging these unique cellular models, users can accelerate their investigations into gene function, potentially leading to breakthroughs in therapeutic strategies and diagnostic markers.

At our company, we pride ourselves on our expertise in cellular biology and genetic engineering, offering a comprehensive range of high-quality biological products that cater to the diverse needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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