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CDS2 Knockout Cell Lines

Gene: CDS2

Official Full Name: CDP-diacylglycerol synthase 2provided by HGNC

Gene Summary: Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07754 CDS2 Knockout cell line (HeLa) Human CDS2 1:3~1:6 Negative Online Inquiry
KO07755 CDS2 Knockout cell line (HCT 116) Human CDS2 1:2~1:4 Negative Online Inquiry
KO07756 CDS2 Knockout cell line (HEK293) Human CDS2 1:3~1:6 Negative Online Inquiry
KO07757 CDS2 Knockout cell line (A549) Human CDS2 1:3~1:4 Negative Online Inquiry

Background

CDS2 Gene Knockout Cell Lines are genetically modified cell lines designed to lack the CDS2 gene, which encodes for a pivotal enzyme involved in lipid metabolism. These cell lines are produced using advanced gene-editing technologies, such as CRISPR/Cas9, allowing for precise deletion of the CDS2 gene and maintenance of cellular integrity for downstream applications. By eliminating the CDS2 gene, researchers can study the functional consequences of its absence, providing critical insights into metabolic pathways and their roles in various biological processes.

The mechanism of action behind CDS2 loss involves disruption of the biosynthetic pathway for certain lipids, thereby influencing cellular functions, signaling, and energy homeostasis. This alteration allows scientists to elucidate the role of CDS2 in conditions such as metabolic disorders, cancer, and cardiovascular diseases. The importance of these cell lines extends into research and clinical settings, where understanding the implications of lipid metabolism can lead to the discovery of new therapeutic targets and treatment strategies.

One of the unique selling points of CDS2 Gene Knockout Cell Lines is their specificity and reliability. Unlike other generalized knockout models, these lines enable precise and reproducible studies focusing on the CDS2 gene, facilitating high-resolution studies in metabolic research. Furthermore, the consistency across various batches ensures reproducibility, critical for validating scientific findings.

For researchers and clinicians, the value of acquiring CDS2 Gene Knockout Cell Lines rests in their ability to accelerate discoveries in lipid metabolism and associated diseases. These resources enable a deeper understanding of disease mechanisms, supporting the transition from bench to bedside in clinical applications.

With a commitment to cutting-edge research and development, our company prides itself on offering high-quality genetic products tailored to meet the rigorous demands of the scientific community. Our expertise in gene editing technology underpins the reliability and effectiveness of our CDS2 Gene Knockout Cell Lines, making them an essential tool for advancing research in lipid biology.

Please note that all services are for research use only. Not intended for any clinical use.

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