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CDR2 Knockout Cell Lines

Gene: CDR2

Official Full Name: cerebellar degeneration related protein 2provided by HGNC

Gene Summary: Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00879 CDR2 Knockout cell line(OVCAR-3) Human CDR2 1:2~1:3 Negative Online Inquiry
KO18857 CDR2 Knockout cell line (HeLa) Human CDR2 1:3~1:6 Negative Online Inquiry
KO18858 CDR2 Knockout cell line (HCT 116) Human CDR2 1:2~1:4 Negative Online Inquiry
KO18859 CDR2 Knockout cell line (HEK293) Human CDR2 1:3~1:6 Negative Online Inquiry
KO18860 CDR2 Knockout cell line (A549) Human CDR2 1:3~1:4 Negative Online Inquiry

Background

CDR2 Gene Knockout Cell Lines are advanced cellular models engineered to specifically disrupt the expression of the CDR2 gene, a crucial component implicated in neurobiological processes and cellular signaling pathways. These cell lines utilize CRISPR-Cas9 technology to introduce targeted mutations that lead to the complete knockout of CDR2, allowing researchers to effectively study the gene's function and its role in various biological processes.

The primary functions of CDR2 include involvement in neuronal development, synaptic transmission, and potential links to neurodegenerative diseases. By utilizing these knockout cell lines, scientists can elucidate the precise mechanisms through which CDR2 exerts its effects, offering insights into conditions like cerebellar ataxia and other cognitive impairments. The knockout models enable a range of applications, from basic molecular biology studies to drug discovery and therapeutic interventions, making them invaluable in both research and clinical settings.

One distinct advantage of CDR2 Gene Knockout Cell Lines lies in their specificity and reliability. Compared to traditional knockdown methods, such as RNA interference, CRISPR-based knockout offers a permanent alteration of the genome that allows for consistent, reproducible results over extended experimental periods. Additionally, these cell lines can facilitate high-throughput screening, enabling researchers to rapidly assess the effects of various compounds or treatments on cells devoid of CDR2 function.

For researchers and clinicians focusing on neurobiology, these knockout cell lines are indispensable tools for advancing our understanding of neuronal function and disease mechanisms. They empower users to explore therapeutic avenues with greater precision and depth, ultimately leading to breakthroughs in the treatment of neurological disorders.

As a leader in the field of genetic engineering and biological products, our company is committed to delivering high-quality, rigorously validated cell lines that support cutting-edge research. Our expertise in CRISPR technology and a robust portfolio of genetic models ensures that our products meet the highest standards for scientific exploration and application.

Please note that all services are for research use only. Not intended for any clinical use.

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