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CDK18 Knockout Cell Lines

Gene: CDK18

Official Full Name: cyclin dependent kinase 18provided by HGNC

Gene Summary: Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Involved in positive regulation of myelination. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36175 CDK18 Knockout cell line (HeLa) Human CDK18 1:3~1:6 Negative Online Inquiry
KO36176 CDK18 Knockout cell line (HCT 116) Human CDK18 1:2~1:4 Negative Online Inquiry
KO36177 CDK18 Knockout cell line (HEK293) Human CDK18 1:3~1:6 Negative Online Inquiry

Background

CDK18 Gene Knockout Cell Lines are genetically engineered model systems that facilitate the study of cyclin-dependent kinase 18 (CDK18) by providing a platform in which this specific gene has been disrupted or "knocked out." This manipulation allows researchers to investigate the biological pathways regulated by CDK18 and to understand its role in cell cycle progression, apoptosis, and other critical cellular processes. The unique mechanism of action involves the use of CRISPR-Cas9 technology, which precisely targets and edits the CDK18 gene, ensuring effective and reliable gene disruption.

The scientific importance of CDK18 Gene Knockout Cell Lines cannot be overstated, as they serve as a valuable tool in both basic research and clinical applications. Researchers can use these cell lines to explore the oncogenic potential of CDK18, assess its involvement in cancer progression, and evaluate the therapeutic implications of targeting CDK18 in various malignancies. Additionally, these models can be employed to screen small molecule inhibitors or to study drug resistance mechanisms, paving the way for novel treatment strategies.

A significant advantage of using our CDK18 Gene Knockout Cell Lines is the reproducibility and robustness provided by our standardized protocols, which comply with the highest quality control measures. Unlike other genetic models, which may present variability or incomplete gene knockout, our product guarantees complete disruption and consistent phenotypic expression across batches, ensuring reliable experimental outcomes. This precision saves researchers valuable time and resources in their studies.

For researchers and clinicians alike, investing in CDK18 Gene Knockout Cell Lines represents an opportunity to gain deeper insights into the fundamental biology of cell division and the underlying mechanisms of disease. With access to this essential tool, users can enhance their research endeavors, translating findings into potential clinical applications.

Our company prides itself on its expertise in gene editing technologies and the development of high-quality cellular models. By offering products like the CDK18 Gene Knockout Cell Lines, we are committed to empowering scientific discovery and providing researchers with the tools they need to drive innovation in both academic and clinical settings.

Please note that all services are for research use only. Not intended for any clinical use.

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