Gene: CDK17
Official Full Name: cyclin dependent kinase 17provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jul 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06112 | CDK17 Knockout cell line (HeLa) | Human | CDK17 | 1:3~1:6 | Negative | Online Inquiry |
KO06113 | CDK17 Knockout cell line (HCT 116) | Human | CDK17 | 1:2~1:4 | Negative | Online Inquiry |
KO06114 | CDK17 Knockout cell line (HEK293) | Human | CDK17 | 1:3~1:6 | Negative | Online Inquiry |
KO06115 | CDK17 Knockout cell line (A549) | Human | CDK17 | 1:3~1:4 | Negative | Online Inquiry |
CDK17 Gene Knockout Cell Lines are genetically modified cell lines in which the cyclin-dependent kinase 17 (CDK17) gene has been inactivated through targeted gene disruption techniques. CDK17 plays a pivotal role in the regulation of the cell cycle, gene transcription, and response to various stress signals. By utilizing these knockout cell lines, researchers can investigate the specific contributions of CDK17 to cellular mechanisms such as proliferation, differentiation, and apoptosis. The lack of CDK17 expression provides a unique platform to analyze aberrant signaling pathways that could be implicated in various diseases, including cancer and neurodegenerative disorders.
The primary function of the CDK17 knockout is to facilitate the dissection of its biological roles and elucidate the consequences of its absence on cellular behavior. This is achieved through various experimental approaches, including genomic and proteomic analyses, which enable scientists to explore downstream effectors influenced by CDK17. By observing the phenotypic and molecular changes in these cell lines, researchers can gain valuable insights into CDK17's involvement in cell cycle regulation and transcriptional control.
The significance of CDK17 Gene Knockout Cell Lines extends far beyond basic research. They can be crucial tools in drug discovery and development, particularly for identifying potential targets for therapeutic interventions. In clinical settings, understanding how the modulation of CDK17 affects cellular responses may lead to novel treatments for conditions linked to its dysregulation, thus bridging the gap between bench research and clinical application.
What sets our CDK17 Gene Knockout Cell Lines apart from conventional knockout models is their high specificity and reliability, achieved through state-of-the-art CRISPR/Cas9 gene editing technology. This precise approach ensures minimal off-target effects, allowing researchers to trust their experimental outcomes. Furthermore, our cell lines come with thorough validation data and user-friendly protocols, making them accessible for both experienced and novice researchers alike.
For researchers, clinicians, and pharmaceutical companies, the CDK17 Gene Knockout Cell Lines represent a significant advancement in the exploration of cellular function and disease mechanisms. Our company's commitment to quality and innovation ensures that you have access to reliable biological products that can drive your research and clinical discoveries forward. Whether you are delving into fundamental biology or developing targeted therapies, our CDK17 Gene Knockout Cell Lines will equip you with the tools you need to succeed.
Please note that all services are for research use only. Not intended for any clinical use.
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