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CDK16 Knockout Cell Lines

Gene: CDK16

Official Full Name: cyclin dependent kinase 16provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04805 CDK16 Knockout cell line (HeLa) Human CDK16 1:3~1:6 Negative Online Inquiry
KO04806 CDK16 Knockout cell line (HCT 116) Human CDK16 1:2~1:4 Negative Online Inquiry
KO04807 CDK16 Knockout cell line (HEK293) Human CDK16 1:3~1:6 Negative Online Inquiry
KO04808 CDK16 Knockout cell line (A549) Human CDK16 1:3~1:4 Negative Online Inquiry

Background

CDK16 Gene Knockout Cell Lines are specifically engineered cellular models that have had the cyclin-dependent kinase 16 (CDK16) gene inactivated using advanced gene-editing technologies such as CRISPR-Cas9. This unique product allows researchers to study the specific role of CDK16 in cellular processes, elucidating its involvement in cell cycle regulation, transcriptional control, and signal transduction pathways. By generating these knockout models, scientists can analyze phenotypic changes that occur in the absence of CDK16, thereby providing insights into the molecular mechanisms underlying various biological phenomena and disease states.

The primary function of CDK16 is to regulate various cellular processes, including cell proliferation and differentiation. It acts as a kinase that phosphorylates target proteins, impacting signaling pathways essential for cell cycle progression. The CDK16 Gene Knockout Cell Lines provide a powerful tool for investigating how the loss of this kinase affects cellular behavior. By utilizing these knockout lines, researchers can assess the functional consequences of CDK16 in cancer biology, neurobiology, and other fields, leading to potential therapeutic targets.

The scientific importance of these knockout cell lines extends to their applications in drug discovery and development, as well as in fundamental research settings. They allow for robust investigation of CDK16's role in oncogenesis and its potential as a biomarker for cancer prognosis. Furthermore, when combined with high-throughput screening technologies, these cell lines can streamline the identification of novel compounds that modulate CDK16 activity, enhancing the drug development pipeline.

Compared to alternative models, such as RNA interference (RNAi) approaches or transient transfection methods, CDK16 Gene Knockout Cell Lines offer stable and consistent gene inactivation, which is critical for long-term experiments and reliable data. The predictability of these knockout models reduces variability, enabling clearer interpretation of experimental results.

Researchers and clinicians will find CDK16 Gene Knockout Cell Lines invaluable due to the precision they offer in dissecting CDK16 functions. The ability to conduct detailed studies on the implications of CDK16 absence facilitates advancements in biological understanding and therapeutic innovations.

Our company prides itself on its commitment to advancing research by providing high-quality, specialized biological tools. With expertise in genetic engineering and a focus on cellular models, we deliver products that empower scientists to unlock new discoveries in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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