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CDCA5 Knockout Cell Lines

Gene: CDCA5

Official Full Name: cell division cycle associated 5provided by HGNC

Gene Summary: Predicted to enable chromatin binding activity. Involved in chromosome organization; double-strand break repair; and positive regulation of exit from mitosis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00857 CDCA5 Knockout cell line(Hep G2) Human CDCA5 1:2~1:4 Negative Online Inquiry

Background

CDCA5 Gene Knockout Cell Lines are genetically engineered cells that have had the CDCA5 gene—involved in cell cycle regulation—silenced or disrupted. This innovative product facilitates the detailed study of CDCA5's role in cellular processes such as mitosis, apoptosis, and genomic stability. By employing advanced CRISPR/Cas9 or other gene-editing technologies, these cell lines provide a powerful tool for researchers to investigate how alterations in CDCA5 expression can impact tumorigenesis and other diseases characterized by abnormal cell proliferation.

The primary function of these knockout cell lines lies in their ability to mimic pathological conditions where CDCA5 is dysregulated, allowing for in-depth analysis of downstream effects on cell cycle checkpoints and DNA repair mechanisms. Researchers can efficiently assess various cellular outcomes, including changes in proliferation rates, apoptotic responses, and susceptibility to chemotherapeutic agents. This makes CDCA5 knockout cell lines invaluable in translational research aimed at developing targeted cancer therapies and understanding resistance mechanisms.

The scientific importance of these cell lines extends to both academic research and clinical applications, offering insights into how CDCA5 dysfunction underlies various malignancies. They can be utilized in drug discovery processes, where the effects of potential therapeutic compounds on CDCA5-deficient cells can elucidate new treatment strategies for cancer patients, thus bridging basic science with clinical applications.

What sets our CDCA5 Gene Knockout Cell Lines apart from alternative products is our commitment to quality and reproducibility. Each cell line undergoes rigorous validation to confirm the knockout efficiency and characterization, ensuring that researchers receive consistent and reliable models for their studies. Additionally, our comprehensive support, including protocol optimization and troubleshooting assistance, enhances the user experience and facilitates efficient experimental designs.

In summary, CDCA5 Gene Knockout Cell Lines represent a significant advancement for researchers and clinicians seeking to understand the complexities of cell cycle regulation and cancer biology. With our expertise in high-quality biological products, we are dedicated to providing tools that empower scientific discovery and innovation, ultimately contributing to advancements in therapeutics and patient care.

Please note that all services are for research use only. Not intended for any clinical use.

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