Gene: CDC42EP4
Official Full Name: CDC42 effector protein 4provided by HGNC
Gene Summary: The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06731 | CDC42EP4 Knockout cell line (HeLa) | Human | CDC42EP4 | 1:3~1:6 | Negative | Online Inquiry |
KO06732 | CDC42EP4 Knockout cell line (HCT 116) | Human | CDC42EP4 | 1:2~1:4 | Negative | Online Inquiry |
KO06733 | CDC42EP4 Knockout cell line (HEK293) | Human | CDC42EP4 | 1:3~1:6 | Negative | Online Inquiry |
KO06734 | CDC42EP4 Knockout cell line (A549) | Human | CDC42EP4 | 1:3~1:4 | Negative | Online Inquiry |
CDC42EP4 Gene Knockout Cell Lines are genetically modified cell lines in which the CDC42EP4 gene, also known as the CDC42 effector protein 4, has been selectively disrupted. This product serves as an invaluable tool for researchers focusing on the role of the CDC42EP4 protein in cellular processes such as cytoskeletal dynamics, cell migration, and signal transduction pathways. By providing a means to investigate the functional consequences of the absence of this gene, these knockout cell lines enable study into various diseases, including cancer and neurodegenerative disorders, where CDC42EP4 may play a critical role.
The mechanism of action relies on the gene's inactivation through targeted CRISPR/Cas9 technology, which introduces specific mutations, leading to a loss of protein expression. This loss allows researchers to delineate the pathways and interactions that CDC42EP4 influences, facilitating insights into its biological functions and potential therapeutic targets.
In scientific research and clinical applications, the ability to study gene function at the cellular level is paramount. These knockout cell lines provide a controlled environment to observe phenotypic changes and molecular disruptions that mimic pathological states, thereby accelerating drug discovery processes and the identification of novel interventions or biomarkers.
One of the significant advantages of using our CDC42EP4 Gene Knockout Cell Lines lies in their stability and reproducibility, ensuring that experimental results are both reliable and valid. Compared to traditional methods of gene silencing, such as RNA interference, knockout cell lines offer a more permanent solution, leading to deeper insights into gene function. Furthermore, our product is meticulously validated through rigorous quality control protocols, providing researchers with confidence in its efficacy and performance.
Ultimately, the CDC42EP4 Gene Knockout Cell Lines represent a vital resource for researchers and clinicians aiming to advance the understanding of CDC42EP4-related mechanisms in health and disease. With our expertise in genetic engineering and commitment to innovation, we offer unparalleled support and a robust product portfolio to meet the evolving demands of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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