Home / CCDC88A Knockout Cell Lines

CCDC88A Knockout Cell Lines

Gene: CCDC88A

Official Full Name: coiled-coil domain containing 88Aprovided by HGNC

Gene Summary: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06194 CCDC88A Knockout cell line (HeLa) Human CCDC88A 1:3~1:6 Negative Online Inquiry
KO06195 CCDC88A Knockout cell line (HCT 116) Human CCDC88A 1:2~1:4 Negative Online Inquiry
KO06196 CCDC88A Knockout cell line (HEK293) Human CCDC88A 1:3~1:6 Negative Online Inquiry
KO06197 CCDC88A Knockout cell line (A549) Human CCDC88A 1:3~1:4 Negative Online Inquiry

Background

CCDC88A Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate the investigation of the CCDC88A gene, which encodes for a protein involved in various cellular processes, including cytoskeletal organization and cell signaling. These knockout cell lines are generated through cutting-edge CRISPR-Cas9 technology, ensuring precise disruption of the CCDC88A gene, allowing researchers to study its functional roles by assessing phenotypic and biochemical changes in the absence of this critical protein.

The key functions of CCDC88A are associated with its role in regulating microtubule dynamics, influencing cell motility, and participating in intracellular signaling pathways. The knockout model allows researchers to delineate the specific pathways and mechanisms that CCDC88A impacts, thus providing insights into cellular behaviors such as proliferation, migration, and differentiation. This capability makes the CCDC88A Gene Knockout Cell Lines particularly valuable for studies in cancer research, neurobiology, and developmental biology, where aberrations in cellular signaling can lead to pathologies.

One of the significant advantages of utilizing these knockout cell lines is their potential for high specificity in experimental results compared to conventional methods like RNA interference, which can elicit off-target effects. The precision of CRISPR-Cas9 technology ensures that researchers have a reliable tool for dissecting complex biological questions related to CCDC88A functionality, making it an invaluable asset in both academic and clinical research endeavors.

For researchers and clinicians, the ability to employ CCDC88A Gene Knockout Cell Lines means they can perform robust investigations into disease mechanisms and explore potential therapeutic targets with greater confidence and accuracy. This tool enhances the understanding of CCDC88A’s role in critical pathways and could lead to novel interventions for associated diseases.

At [Your Company Name], we are dedicated to advancing the field of molecular biology through high-quality, innovative products. Our expertise in gene editing technologies positions us as a trusted partner for researchers seeking to elevate their studies with reliable and precise biological tools.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.