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CCDC80 Knockout Cell Lines

Gene: CCDC80

Official Full Name: coiled-coil domain containing 80provided by HGNC

Gene Summary: Predicted to enable fibronectin binding activity and heparin binding activity. Predicted to be involved in extracellular matrix organization and positive regulation of cell-substrate adhesion. Predicted to act upstream of or within response to bacterium. Predicted to be located in extracellular region; interstitial matrix; and membrane. Predicted to be active in basement membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00437 CCDC80 gRNA1-gRNA2 KO plasmid CCDC80 $850
KO00736 CCDC80 Knockout cell line (Hep G2) Human CCDC80 1:2~1:4 Negative Online Inquiry
KO18995 CCDC80 Knockout cell line (HeLa) Human CCDC80 1:3~1:6 Negative Online Inquiry
KO18996 CCDC80 Knockout cell line (HEK293) Human CCDC80 1:3~1:6 Negative Online Inquiry
KO18997 CCDC80 Knockout cell line (A549) Human CCDC80 1:3~1:4 Negative Online Inquiry

Background

CCDC80 Gene Knockout Cell Lines consist of genetically modified cell lines in which the CCDC80 (Coiled-Coil Domain Containing 80) gene has been selectively disrupted, facilitating in-depth studies of its biological functions and related pathways. This targeted gene knockout allows researchers to investigate the role of CCDC80 in cellular processes such as adhesion, proliferation, and response to external stimuli, effectively providing a powerful tool for functional genomics.

The key functionality of CCDC80 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for assessing the implications of CCDC80 absence on various biological phenomena. Mechanistically, the knockout induces physiological changes that can unveil the gene's contributions to cellular signaling pathways, particularly those involved in cancer biology and tissue homeostasis. The ability to utilize these cell lines enables scientists to systematically dissect molecular interactions and gene dependencies, ultimately yielding insights that may translate into therapeutic advancements.

The scientific importance of these knockout cell lines is evident in research focused on tumorigenesis, metastasis, and development, where understanding CCDC80’s role can uncover new potential targets for intervention. Their applications extend to both in vitro studies and high-throughput screening strategies in drug development, underscoring the versatility of these models in diverse research settings.

What sets CCDC80 Gene Knockout Cell Lines apart from alternative products is their validated knockout efficiency and compatibility with various assays including proliferation, migration, and invasion assays. Additionally, these lines are rigorously characterized, providing researchers with confidence in reproducibility and reliability of experimental results.

For researchers and clinicians aiming to identify novel molecular targets for disease treatment or gain insights into fundamental biological processes, CCDC80 Gene Knockout Cell Lines are an invaluable resource. The precision of these models facilitates cutting-edge research, enhancing the potential for breakthroughs in understanding complex biological networks.

Leveraging our extensive expertise in genetic engineering, our company is committed to providing high-quality, readily available biological tools that empower scientists and clinicians to advance their research and clinical outcomes. Our portfolio exemplifies innovation and reliability, ensuring users can focus on their pivotal work in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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