Gene: CCDC47
Official Full Name: coiled-coil domain containing 47provided by HGNC
Gene Summary: Enables protein folding chaperone and ribosome binding activity. Involved in ERAD pathway; endoplasmic reticulum calcium ion homeostasis; and multi-pass transmembrane protein insertion into ER membrane. Located in endoplasmic reticulum membrane. Part of multi-pass translocon complex and protein folding chaperone complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19022 | CCDC47 Knockout cell line (HeLa) | Human | CCDC47 | 1:3~1:6 | Negative | Online Inquiry |
KO19023 | CCDC47 Knockout cell line (HCT 116) | Human | CCDC47 | 1:2~1:4 | Negative | Online Inquiry |
KO19024 | CCDC47 Knockout cell line (HEK293) | Human | CCDC47 | 1:3~1:6 | Negative | Online Inquiry |
KO19025 | CCDC47 Knockout cell line (A549) | Human | CCDC47 | 1:3~1:4 | Negative | Online Inquiry |
CCDC47 Gene Knockout Cell Lines are genetically modified cell lines in which the CCDC47 gene has been targeted and disrupted. This modification results in the ablation of the functions associated with the CCDC47 protein, which is integral to normal cellular processes including the regulation of immune response and cellular homeostasis. The precise mechanisms underlying the changes in phenotype can provide insights into the intricate molecular pathways that the CCDC47 gene influences.
By employing CRISPR-Cas9 technology or siRNA approaches, the CCDC47 knockout model allows researchers to dissect the functional consequences of this gene’s loss in various biological contexts. These cell lines serve as pivotal tools for elucidating the role of CCDC47 in cellular processes and its involvement in disease pathophysiology, particularly in cancer and immune disorders. Their applicability spans across fundamental research, drug discovery, and the development of targeted therapies, significantly impacting our understanding of cellular dynamics in both normal and pathological states.
The key advantages of the CCDC47 Gene Knockout Cell Lines lie in their specificity and reliability. Unlike alternative methods that may introduce off-target effects or yield varying expression levels, the knockout approach provides a clear, consistent model for studying the CCDC47 gene. This precision equips researchers with a solid foundation to verify their hypotheses and experiments, minimizing data variability and enhancing reproducibility.
Furthermore, these cell lines come with detailed characterization data, enabling users to quickly assess their suitability for diverse experimental designs. The time-saving nature of utilizing pre-established cell lines can be invaluable to researchers aiming to accelerate their studies without compromising on scientific rigor.
Our company has extensive expertise in genetic editing technologies and a commitment to providing high-quality biological products. We understand the challenges faced by researchers and clinicians, and we aim to support advancements in life sciences by offering reliable, genetically modified cell lines like the CCDC47 Gene Knockout variants, designed to facilitate breakthroughs in research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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