Gene: CCDC28A
Official Full Name: coiled-coil domain containing 28Aprovided by HGNC
Gene Summary: This gene encodes a coiled-coil domain containing protein. Although the specific function of this gene has not yet been determined, this gene is a known translocation partner of nucleoporin 98 in acute leukemias. The resulting fusion gene produces a nucleoporin 98-coiled-coil domain-containing protein 28A chimeric protein which may be involved in promoting myeloproliferative neoplasms. [provided by RefSeq, Jan 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28659 | CCDC28A Knockout cell line (HeLa) | Human | CCDC28A | 1:3~1:6 | Negative | Online Inquiry |
KO28660 | CCDC28A Knockout cell line (HCT 116) | Human | CCDC28A | 1:2~1:4 | Negative | Online Inquiry |
KO28661 | CCDC28A Knockout cell line (HEK293) | Human | CCDC28A | 1:3~1:6 | Negative | Online Inquiry |
KO28662 | CCDC28A Knockout cell line (A549) | Human | CCDC28A | 1:3~1:4 | Negative | Online Inquiry |
CCDC28A Gene Knockout Cell Lines are genetically modified cell lines created to facilitate the study of the CCDC28A gene, which has been implicated in various cellular processes, including cilia formation and cellular migration. These knockout models are essential for elucidating the gene's specific functions and mechanisms as they are designed to lack the functional CCDC28A protein, thereby enabling researchers to observe phenotypic changes that arise from its absence.
The primary mechanism at play within these knockout cell lines involves the targeted deletion of the CCDC28A gene using CRISPR/Cas9 technology, a method that ensures high specificity and efficiency in gene editing. This allows researchers to investigate the pathways and molecular interactions influenced by the CCDC28A protein, including its role in cell cycle regulation and potential implications in ciliopathies.
In terms of scientific importance, CCDC28A Gene Knockout Cell Lines serve as powerful tools in both basic and applied research settings. They can contribute to understanding disease mechanisms, particularly in developmental biology and regenerative medicine, as well as in drug discovery processes where modulators of the pathways involving CCDC28A may be identified. Their application extends to clinical research, where insights gained might lead to novel therapeutic interventions targeting conditions associated with cilia dysfunction.
One of the notable advantages of utilizing CCDC28A Gene Knockout Cell Lines is their reliability and reproducibility in experimental outcomes, attributes that are critical when comparing data across different studies. Compared to other alternatives, such as transient knockdown methods, these knockout cell lines offer a permanent solution for long-term investigations, thus increasing the reliability of experimental results.
For researchers and clinicians seeking to deepen their understanding of CCDC28A-related pathways, these knockout cell lines represent an invaluable resource. They not only streamline the investigational process but also enhance the precision of experiments derived from genetic models.
Our company specializes in providing high-quality genetic tools and resources to the scientific community. With our expertise in gene editing technologies and commitment to supporting innovative research, we are dedicated to empowering researchers with reliable models that advance science.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.