Gene: CCDC138
Official Full Name: coiled-coil domain containing 138provided by HGNC
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18958 | CCDC138 Knockout cell line (HeLa) | Human | CCDC138 | 1:3~1:6 | Negative | Online Inquiry |
KO18959 | CCDC138 Knockout cell line (HCT 116) | Human | CCDC138 | 1:2~1:4 | Negative | Online Inquiry |
KO18960 | CCDC138 Knockout cell line (HEK293) | Human | CCDC138 | 1:3~1:6 | Negative | Online Inquiry |
KO18961 | CCDC138 Knockout cell line (A549) | Human | CCDC138 | 1:3~1:4 | Negative | Online Inquiry |
CCDC138 Gene Knockout Cell Lines represent a cutting-edge biological tool designed to facilitate the study of gene function and its implications in various cellular processes. These cell lines are generated through advanced CRISPR-Cas9 gene editing technology, effectively disabling the CCDC138 gene, which is implicated in critical cellular mechanisms including cell adhesion and signaling pathways.
The primary mechanism by which CCDC138 Knockout Cell Lines operate is through the precise introduction of double-strand breaks in the DNA at targeted sequences of the CCDC138 gene. The cellular repair machinery, in an attempt to correct these breaks, often introduces deletion mutations, leading to a nonfunctional gene product. This targeted disruption allows researchers to study the resultant phenotypic changes and understand the role CCDC138 plays in cellular behavior, contributing to the ongoing efforts in elucidating gene pathways involved in disease.
The scientific importance of CCDC138 Gene Knockout Cell Lines cannot be overstated, particularly in research settings focused on cancer biology, developmental biology, and regenerative medicine. By providing an effective model to study the consequences of CCDC138 loss, these cell lines help to uncover potential therapeutic targets and provide insights into the pathogenesis of diseases associated with this gene.
Compared to alternative gene editing methods, such as RNA interference, CRISPR-Cas9 offers several distinct advantages. These include enhanced efficiency and specificity, allowing for clean gene deletions and the potential for multiplexing, where multiple genes can be knocked out simultaneously. Moreover, the stable nature of the knockout cell lines allows for long-term studies and reproducibility in experimental settings.
For researchers and clinicians, the value of CCDC138 Gene Knockout Cell Lines lies in their ability to foster innovative discoveries and advance our understanding of complex biological systems. The product is designed to meet the rigorous standards expected in the scientific community, thus representing a reliable choice for high-quality research.
Our company prides itself on its commitment to advancing biomedical research through the provision of specialized tools such as gene knockout cell lines. With expertise in gene editing technology and a focus on quality, we continue to support the scientific community in advancing knowledge and unlocking the mysteries of gene function.
Please note that all services are for research use only. Not intended for any clinical use.
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