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CC2D2A Knockout Cell Lines

Gene: CC2D2A

Official Full Name: coiled-coil and C2 domain containing 2Aprovided by HGNC

Gene Summary: This gene encodes a coiled-coil and calcium binding domain protein that appears to play a critical role in cilia formation. Mutations in this gene cause Meckel syndrome type 6, as well as Joubert syndrome type 9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19046 CC2D2A Knockout cell line (HeLa) Human CC2D2A 1:3~1:6 Negative Online Inquiry
KO19047 CC2D2A Knockout cell line (HCT 116) Human CC2D2A 1:2~1:4 Negative Online Inquiry
KO19048 CC2D2A Knockout cell line (HEK293) Human CC2D2A 1:3~1:6 Negative Online Inquiry
KO19049 CC2D2A Knockout cell line (A549) Human CC2D2A 1:3~1:4 Negative Online Inquiry

Background

CC2D2A Gene Knockout Cell Lines are a specialized series of genetically modified cell lines where the CC2D2A gene has been disrupted, resulting in a functional knockout. CC2D2A is known to play a crucial role in ciliary function and development, making these cell lines an invaluable tool for studying ciliary-related pathways and associated disorders. By creating these knockout models, researchers can effectively investigate the cellular mechanisms that govern cilia formation, function, and their implications in various diseases, including ciliopathies.

The primary mechanism by which the CC2D2A knockout operates is through the ablation of CC2D2A protein expression, allowing investigators to observe the downstream effects on signaling pathways that are reliant on ciliary activity. This leads to a profound understanding of the role of CC2D2A in cell cycle regulation, intracellular transport, and cell signaling — facets that are often altered in pathogenic conditions.

The scientific importance of CC2D2A Gene Knockout Cell Lines cannot be overstated, as they facilitate groundbreaking research in developmental biology, genetics, and disease modeling. Their utility extends to drug discovery and efficacy testing, providing insights that could lead to the identification of novel therapeutic targets for treatments aimed at ciliary dysfunction.

When compared to alternative cell models, CC2D2A Gene Knockout Cell Lines present several advantages, such as their specificity in targeting the CC2D2A gene, which significantly enhances the precision of experimental outcomes. In addition, the ease of use and reproducibility of these knockout models allow for consistent results, further stimulating high-quality research.

These cell lines offer remarkable value to researchers, clinicians, and biotechnology companies by bridging the gap between basic science and clinical application. By using these knockout models, researchers can deepen their understanding of complex diseases and potentially expedite the development of new interventions.

Our company is committed to advancing scientific research through innovative biological products, and our expertise in genetic engineering ensures the delivery of high-quality gene knockout models, tailored to meet the rigorous demands of contemporary biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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