Gene: CAMSAP2
Official Full Name: calmodulin regulated spectrin associated protein family member 2provided by HGNC
Gene Summary: Enables microtubule minus-end binding activity. Involved in several processes, including axon development; regulation of dendrite development; and regulation of organelle organization. Located in Golgi apparatus; cytosol; and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29560 | CAMSAP2 Knockout cell line (HeLa) | Human | CAMSAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO29561 | CAMSAP2 Knockout cell line (HCT 116) | Human | CAMSAP2 | 1:2~1:4 | Negative | Online Inquiry |
KO29562 | CAMSAP2 Knockout cell line (HEK293) | Human | CAMSAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO29563 | CAMSAP2 Knockout cell line (A549) | Human | CAMSAP2 | 1:3~1:4 | Negative | Online Inquiry |
CAMSAP2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the CAMSAP2 gene, which is known to play a significant role in microtubule organization and cellular dynamics. These knockout cell lines are critical tools for investigating the functional contributions of CAMSAP2 to various cellular processes, including cell proliferation, differentiation, and migration. By completely removing the transcriptional activity of the CAMSAP2 gene, researchers gain insight into the downstream effects on cell morphology and behavior, as well as alterations in cytoskeletal structures.
The primary function of CAMSAP2 involves the stabilization of microtubules at the cell's minus ends, thereby influencing the dynamics of the microtubule network. When this gene is knocked out, perturbations in microtubule organization may lead to enhanced insights into disease mechanisms such as cancer progression and neurodegenerative disorders, where microtubule stability is often compromised. This specificity allows for controlled studies of the CAMSAP2 protein's role, enabling researchers to elucidate potential pathways for therapeutic intervention.
Scientifically, CAMSAP2 Gene Knockout Cell Lines are invaluable in both basic research and clinical settings. They provide a robust model for identifying new drug targets, understanding disease mechanisms, and developing therapeutic strategies aimed at restoring normal cell function. In comparison to other genetic modification technologies, such as CRISPR/Cas9, the targeted deletion achieved with our CAMSAP2 cell lines ensures a complete loss of function, providing a clear and definitive model for studies.
The specific advantages of our CAMSAP2 Gene Knockout Cell Lines include their validated performance across diverse experimental conditions, consistent reproducibility, and ease of use in various laboratory settings. These features position our product as a leading option for scientists and clinicians seeking reliable tools to advance their research.
Our company, with its extensive expertise in developing advanced genetic models, is committed to delivering high-quality products that empower researchers and contribute to the advancement of biological sciences. We stand by the reliability and efficacy of our CAMSAP2 Gene Knockout Cell Lines as fundamental assets in today's innovative research environment.
Please note that all services are for research use only. Not intended for any clinical use.
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