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CAMK1D Knockout Cell Lines

Gene: CAMK1D

Official Full Name: calcium/calmodulin dependent protein kinase IDprovided by HGNC

Gene Summary: This gene is a member of the calcium/calmodulin-dependent protein kinase 1 family, a subfamily of the serine/threonine kinases. The encoded protein is a component of the calcium-regulated calmodulin-dependent protein kinase cascade. It has been associated with multiple processes including regulation of granulocyte function, activation of CREB-dependent gene transcription, aldosterone synthesis, differentiation and activation of neutrophil cells, and apoptosis of erythroleukemia cells. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jan 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07964 CAMK1D Knockout cell line (HeLa) Human CAMK1D 1:3~1:6 Negative Online Inquiry
KO07965 CAMK1D Knockout cell line (HCT 116) Human CAMK1D 1:2~1:4 Negative Online Inquiry
KO07966 CAMK1D Knockout cell line (HEK293) Human CAMK1D 1:3~1:6 Negative Online Inquiry
KO07967 CAMK1D Knockout cell line (A549) Human CAMK1D 1:3~1:4 Negative Online Inquiry

Background

CAMK1D Gene Knockout Cell Lines are genetically engineered cell lines that have undergone targeted gene disruption of the CAMK1D (Calcium/Calmodulin-dependent protein kinase type 1D) gene. This alteration facilitates the study of the gene's functional role in various cellular processes, including calcium signaling, cell proliferation, and apoptosis. By removing the CAMK1D gene, researchers can explore its contributions to physiological and pathological conditions, enhancing the understanding of its potential implications in diseases such as cancer, neurodegenerative disorders, and cardiovascular ailments.

The key function of CAMK1D gene knockout cell lines lies in their ability to serve as a powerful tool for dissecting complex biological pathways. These cell lines exhibit altered activation of downstream signaling cascades, providing insights into the mechanistic roles of CAMK1D in cellular responses. The absence of functional CAMK1D allows researchers to assess compensatory mechanisms, thus leading to a comprehensive understanding of the signaling networks involved in health and disease.

The scientific importance of these knockout cell lines extends to both research and clinical settings. In laboratory experiments, they provide a precise model for studying the effects of targeted therapies, genetic interactions, and drug responses. Clinically, insights gained from investigating CAMK1D function may pave the way for developing novel therapeutic strategies for diseases characterized by dysregulated calcium signaling and aberrant cellular growth.

Compared to alternatives such as traditional wild-type cell lines or non-targeted gene disruptions, CAMK1D gene knockout cell lines offer unrivaled specificity and consistency in experimental outcomes. Researchers can rely on these tailored models to deliver precise data that is crucial for translating findings into clinical applications.

For researchers and clinicians seeking reliable and relevant cellular models, CAMK1D gene knockout cell lines represent an invaluable resource for advancing scientific knowledge and therapeutic development. Our company's commitment to providing high-quality biological products is firmly backed by our expertise in genetic engineering and our focus on innovative solutions that meet the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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