Gene: CACUL1
Official Full Name: CDK2 associated cullin domain 1provided by HGNC
Gene Summary: Enables protein kinase binding activity. Involved in G1/S transition of mitotic cell cycle; positive regulation of cell population proliferation; and positive regulation of protein kinase activity. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24228 | CACUL1 Knockout cell line (HeLa) | Human | CACUL1 | 1:3~1:6 | Negative | Online Inquiry |
KO24229 | CACUL1 Knockout cell line (HCT 116) | Human | CACUL1 | 1:2~1:4 | Negative | Online Inquiry |
KO24230 | CACUL1 Knockout cell line (HEK293) | Human | CACUL1 | 1:3~1:6 | Negative | Online Inquiry |
KO24231 | CACUL1 Knockout cell line (A549) | Human | CACUL1 | 1:3~1:4 | Negative | Online Inquiry |
CACUL1 Gene Knockout Cell Lines are advanced research tools designed for studying the functional implications of the CACUL1 gene in various biological processes. These cell lines are genetically modified to lack the expression of the CACUL1 gene, enabling researchers to investigate the cellular and molecular mechanisms associated with its absence. The knockout model allows scientists to study alterations in cellular pathways, gene expression profiles, and responses to various stimuli, providing vital insights into the role of CACUL1 in health and disease.
The mechanism underlying these cell lines involves the targeted disruption of the CACUL1 gene through precise genome editing techniques such as CRISPR/Cas9. This results in the complete knockout of gene activity, thereby facilitating the exploration of phenotypic changes. Researchers can utilize these cell lines to uncover the gene's involvement in processes such as cell proliferation, apoptosis, and signal transduction pathways, which may offer clues about its potential role in pathological conditions, including cancer and other genetic disorders.
Scientifically, the CACUL1 Gene Knockout Cell Lines serve as essential tools in both basic research and therapeutic development. They are invaluable for drug discovery applications, offering a platform for screening potential therapeutic agents and identifying novel targets. Furthermore, these cell lines can contribute to understanding drug resistance mechanisms, enhancing the development of more effective treatment protocols.
Compared to alternative models, the CACUL1 Gene Knockout Cell Lines provide several advantages. They offer a high degree of specificity and reliability, ensuring that any observed effects can be attributed to the absence of the CACUL1 gene. Additionally, these cell lines can be easily manipulated and expanded, making them suitable for large-scale experiments and high-throughput screening methodologies.
For researchers, clinicians, and biotechnology companies, the CACUL1 Gene Knockout Cell Lines represent a powerful asset for advancing our understanding of gene function and its implications in disease. Their ability to provide insights into complex biological questions can elevate research outcomes and facilitate innovative therapeutic discoveries.
Our company prides itself on its expertise in developing cutting-edge biological products that empower the scientific community. With a commitment to quality and innovation, we strive to support researchers in their quest to uncover new knowledge and drive advancements in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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